STRINGSTRING
UGD1 protein (Arabidopsis thaliana) - STRING interaction network
"UGD1" - UDP-glucose dehydrogenase 1 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UGD1UDP-glucose dehydrogenase 1; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers (481 aa)    
Predicted Functional Partners:
USP
UDP-sugar pyrophosphorylase; Required for the synthesis of the intine, the pectocellulosic inner wall of developing pollen. May function as the terminal enzyme of the myo-inositol oxidation (MIO) pathway. May also play a role in the salvage pathway for synthesis of nucleotide sugars (PubMed-16557401, PubMed-16757173, PubMed-23373795). Can use a wide range of substrates including glucose-1-phosphate, galactose-1-phospate, xylose-1-phospate, arabinose-1-phospate and glucuronate-1-phospate (PubMed-17341835) (614 aa)
         
  0.987
GLCAK
Glucuronokinase G; Sugar-1-kinase with a strict substrate specificity for D-glucuronic acid and ATP. Involved in the biosynthesis of UDP- glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell- wall polymers. May be also involved in a salvage pathway for glucuronic acid (362 aa)
           
  0.980
AUD1
UDP-glucuronic acid decarboxylase; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (445 aa)
   
 
  0.977
UXS1
UDP-glucuronic acid decarboxylase 1 (458 aa)
   
 
  0.977
UXS4
UDP-xylose synthase 4; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity) (449 aa)
   
 
  0.977
UXS3
UDP-glucuronic acid decarboxylase 3; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (357 aa)
   
 
  0.976
GAE1
UDP-D-glucuronate 4-epimerase; Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components (429 aa)
   
 
  0.976
GAE5
UDP-D-glucuronate 4-epimerase; Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components (436 aa)
   
 
  0.976
GAE3
UDP-D-glucuronate 4-epimerase 3; Involved in the synthesis of the negatively charged monosaccharide that forms the backbone of pectic cell wall components (430 aa)
   
 
  0.976
UXS5
UDP-XYL synthase 5; Catalyzes the NAD-dependent decarboxylation of UDP- glucuronic acid to UDP-xylose. Necessary for the biosynthesis of the core tetrasaccharide in glycosaminoglycan biosynthesis (By similarity) (341 aa)
   
 
  0.976
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (10%) [HD]