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AT1G27590 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G27590" - At1g27590 in Arabidopsis thaliana
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AT1G27590At1g27590; Contains the following InterPro domains- Protein of unknown function DUF3453 (InterPro-IPR021850); BEST Arabidopsis thaliana protein match is- phosphatidylinositol 3- and 4-kinase family protein (TAIR-AT1G27570.1); Has 109 Blast hits to 109 proteins in 38 species- Archae - 0; Bacteria - 0; Metazoa - 65; Fungi - 4; Plants - 38; Viruses - 0; Other Eukaryotes - 2 (source- NCBI BLink) (264 aa)    
Predicted Functional Partners:
CPSF100
Encodes a protein similar to the 100kD subunit of cleavage and polyadenylation specificity factor (CPSF), the factor responsible for the recognition of the AAUAAA motif during mRNA polyadenylation. The protein interacts with a portion of a nuclear poly(A) polymerase. It is likely to be a part of the mRNA 3’end formation apparatus (739 aa)
     
  0.999
CSTF64
Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3’ non-coding region. Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (461 aa)
     
  0.999
CSTF77
Tetratricopeptide repeat (TPR)-like superfamily protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (734 aa)
     
  0.999
CPSF160
Cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction; Belongs to the CPSF1 family (1442 aa)
     
  0.999
FIP1[V]
Homolog of yeast FIP1 [V]; Essential gene. Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) (1196 aa)
     
  0.997
PAPS3
Nuclear poly(A) polymerase 3; Essential protein. Polymerase that creates the 3’-poly(A) tail of mRNA’s. Also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. May acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus (By similarity) (507 aa)
     
  0.994
CPSF73-I
Cleavage and polyadenylation specificity factor subunit 3-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3’-end- processing endonuclease and also be involved in the histone 3’-end pre-mRNA processing (693 aa)
     
  0.994
FY
Transducin/WD40 repeat-like superfamily protein; Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for the negative autoregulation of FCA expression. Acts probably as an RNA 3’ end-processing factor. Required for growth and development in plants (653 aa)
     
  0.992
AT5G60940
Transducin/WD40 repeat-like superfamily protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs. May be responsible for the interaction of CSTF with other factors to form a stable complex on the pre-mRNA (429 aa)
     
 
  0.992
AT2G36480
Pre-mRNA cleavage complex 2 Pcf11-like protein; ENTH/VHS family protein; Its function is described as zinc ion binding; Involved in biological_process unknown; Located in intracellular; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Protein of unknown function DUF618 (InterPro-IPR006903), RNA polymerase II, large subunit, CTD (InterPro-IPR006569), Zinc finger, C2H2-type (InterPro-IPR007087), ENTH/VHS (InterPro-IPR008942); BEST Arabidopsis thaliana protein match is- PCF11P-similar protein 4 (TAIR-AT4G04885.1); Has 1695 Blast [...] (886 aa)
     
  0.992
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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