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AT1G27595 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G27595" - Symplekin in Arabidopsis thaliana
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G27595Symplekin (961 aa)    
Predicted Functional Partners:
CSTF77
Tetratricopeptide repeat-containing protein; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-19965720) (734 aa)
     
 
  0.989
CPSF160
Cleavage and polyadenylation specificity factor 160; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (1442 aa)
     
 
  0.989
FIP1[V]
FIP1 [V]-like protein; Essential gene (PubMed-16282318). Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex (By similarity) (1196 aa)
     
 
  0.988
CPSF100
Cleavage and polyadenylation specificity factor 100; CPSF plays a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Required for antisense-RNA- mediated gene silencing (PubMed-17008405) (739 aa)
     
 
  0.982
CPSF30
Cleavage and polyadenylation specificity factor 30; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation. May interact with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition (By similarity). Mediates poly(A) site selection (PubMed-23136375). Binds RNA in a calcium-dependent manner (PubMed-16500995, PubMed-17576667, PubMed-20214900). Exhibits endonuclease activity with an ability to nick and degrade linear as well as circular single-stranded RNA that leaves RNA 3’ ends with hydro [...] (631 aa)
     
 
  0.972
CSTF64
Cleavage stimulating factor 64; One of the multiple factors required for polyadenylation and 3’-end cleavage of pre-mRNAs (By similarity). This subunit is directly involved in the binding to pre-mRNAs, especially on the 3’ non-coding region (PubMed-12379796). Required for the targeted 3’ processing of antisense transcripts that triggers transcriptional silencing of the corresponding sense gene (PubMed-17008405, PubMed-19965720) (461 aa)
     
 
  0.971
AT1G73820
Ssu72-like protein (193 aa)
       
 
  0.969
CPSF73-I
Cleavage and polyadenylation specificity factor 73-I; Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3’-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. May function as mRNA 3’-end- processing endonuclease and also be involved in the histone 3’-end pre-mRNA processing (693 aa)
     
 
  0.965
FY
Flowering time control protein FY; Plays a role in the regulation of flowering time in the autonomous flowering pathway by decreasing FLOWERING LOCUS C mRNA levels. Required for the negative autoregulation of FCA expression. Acts probably as an RNA 3’ end-processing factor. Required for growth and development in plants (653 aa)
     
 
  0.960
emb2746
Embryo defective 2746 (911 aa)
     
 
  0.953
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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