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ATCSA-1 protein (Arabidopsis thaliana) - STRING interaction network
"ATCSA-1" - transducin/WD-40 repeat-containing protein in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ATCSA-1transducin/WD-40 repeat-containing protein (451 aa)    
Predicted Functional Partners:
DDB1A
DNA damage-binding protein 1a; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis- promoting factors such as HY5, HYH and LAF1. Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB). Component of the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protei [...] (1088 aa)
     
  0.999
DDB1B
DNA damage-binding protein 1b; Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness (By similarity). Plays a role in DNA repair by forming with DDB2 the UV-damaged DNA-binding protein complex (UV-DDB) (By similarity) (1088 aa)
     
  0.994
CUL4
Cullin4; Component of the CUL4-RBX1-CDD (COP10-DDB1a-DET1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Participates in the CDD complex to light-mediated control of development. May repress photomorphogenesis through enhancing COP1 E3 ubiquitin-protein ligase activity. Acts together with the CUL4- DDB1-COP1-SPA E3 ubiquitin-protein ligase complexes in the repression of photomorphogenesis and flowering time. Component ot the CUL4-RBX1-DDB1-PRL1 E3 ubiquitin-protein ligase complex which mediates ubiquitin [...] (792 aa)
     
  0.980
UVH3
DNA repair protein UVH3; Putative single-stranded DNA endonuclease involved in nucleotide excision repair (NER) of UV- and oxidative damaged DNA. May make the 3’-incision step in NER. Seems to play a role in senescence program (1479 aa)
     
 
  0.963
UVH6
DNA repair helicase UVH6; Putative ATP-dependent 5’-3’ DNA helicase involved in nucleotide excision repair (NER) of UV-damaged DNA. May open DNA around the damage. Essential during plant growth. May negatively regulate a common response program mediated by UV damage and heat stress, that leads to tissue death and reduced chloroplast function (758 aa)
     
 
  0.963
AT1G19750
DNA excision repair protein ERCC-8 (450 aa)
     
0.960
CSN5B
COP9-signalosome 5B; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity [...] (358 aa)
       
  0.959
CSN5A
COP9 signalosome 5A; Probable protease subunit of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. In the complex, it probably acts as the catalytic center that mediates the cleavage of Nedd8 from cullins. It however has no metalloprotease activity [...] (357 aa)
       
  0.959
GTF2H2
General transcription factor II H2; Component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. Can restore UV resistance in the NER-deficient ssl1-1 yeast mutant (421 aa)
       
  0.948
CHR8
Chromatin remodeling 8; Essential factor involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II- blocking lesions to be rapidly removed from the transcribed strand of active genes. Upon DNA-binding, it locally modifies DNA conformation by wrapping the DNA around itself, thereby modifying the interface between stalled RNA polymerase II and DNA. It is required for transcription-coupled repair complex formation (1187 aa)
     
  0.945
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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