• Version:
  • 11.0 (preview - - version 10.5 still available here)
PUP3 protein (Arabidopsis thaliana) - STRING interaction network
"PUP3" - Purine permease 3 in Arabidopsis thaliana
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
PUP3Purine permease 3; Member of a family of proteins related to PUP1, a purine transporter. May be involved in the transport of purine and purine derivatives such as cytokinins, across the plasma membrane (351 aa)    
Predicted Functional Partners:
Encodes a uclacyanin, a protein precursor that is closely related to precursors of stellacyanins and a blue copper protein from pea pods (261 aa)
Concanavalin A-like lectin protein kinase family protein; Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici; In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family (668 aa)
Protein kinase protein with adenine nucleotide alpha hydrolases-like domain; Its function is described as kinase activity; Involved in protein amino acid phosphorylation, response to stress; Expressed in 12 plant structures; Expressed during 8 growth stages; Contains the following InterPro domains- UspA (InterPro-IPR006016), Serine/threonine-protein kinase domain (InterPro-IPR002290), Serine-threonine/tyrosine-protein kinase (InterPro-IPR001245), Serine/threonine-protein kinase, active site (InterPro-IPR008271), Protein kinase-like domain (InterPro-IPR011009), Rossmann-like alpha/beta/ [...] (754 aa)
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Binds GDP and GTP, and has low GTPase activity (399 aa)
Uncharacterized protein AT4g30590; Early nodulin-like protein 12 (ENODL12); Its function is described as electron carrier activity, copper ion binding; Located in anchored to membrane; Expressed in 17 plant structures; Expressed during 11 growth stages; Contains the following InterPro domains- Plastocyanin-like (InterPro-IPR003245), Cupredoxin (InterPro-IPR008972); BEST Arabidopsis thaliana protein match is- early nodulin-like protein 11 (TAIR-AT2G23990.1); Has 1418 Blast hits to 1373 proteins in 66 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1418; Viruses - 0; [...] (190 aa)
Rop guanine nucleotide exchange factor 7; Guanine-nucleotide exchange factor (GEF) that acts as an activator of Rop (Rho of plants) GTPases by promoting the exchange of GDP for GTP. In postembryonic roots, modulates root stem cell maintenance by regulating the expression of PLT1 and PLT2, which are key transcription factors that mediate the patterning of the root stem cell niche. May connect RopGEF-regulated Rac/Rop signaling and auxin-dependent PLT-regulated root pattern formation (546 aa)
Eukaryotic aspartyl protease family protein; Its function is described as aspartic-type endopeptidase activity; Involved in proteolysis; Located in endomembrane system; Expressed in shoot apex, hypocotyl, root, leaf; Contains the following InterPro domains- Peptidase aspartic (InterPro-IPR021109), Peptidase aspartic, catalytic (InterPro-IPR009007), Peptidase A1 (InterPro-IPR001461); BEST Arabidopsis thaliana protein match is- Eukaryotic aspartyl protease family protein (TAIR-AT1G03220.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fung [...] (406 aa)
Cytokinin dehydrogenase 5; This gene used to be called AtCKX6. It encodes a protein whose sequence is similar to cytokinin oxidase/dehydrogenase, which catalyzes the degradation of cytokinins (540 aa)
Glutamate receptor 3.2; Glutamate-gated receptor that probably acts as non- selective cation channel. May be involved in light-signal transduction and calcium homeostasis via the regulation of calcium influx into cells. Could play a role in calcium unloading from xylem (912 aa)
Leucine-rich receptor-like protein kinase family protein; Involved in the detection of CLV3 and CLV3-like peptides, that act as extracellular signals regulating meristem maintenance. Acts with CLV3 as a ligand-receptor pair in a signal transduction pathway coordinating growth between adjacent meristematic regions and controlling the balance between meristem cell proliferation and differentiation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family (980 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (7%) [HD]