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AT1G28260 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G28260" - Telomerase activating protein Est1 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G28260Telomerase activating protein Est1; May play a role in growth and development (880 aa)    
Predicted Functional Partners:
Y14
RNA-binding protein 8A (202 aa)
         
  0.958
EIF4A-III
Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity) (408 aa)
         
  0.940
MAGO
MAGO NASHI (150 aa)
         
  0.938
UPF3
Smg-4/UPF3-like protein; Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. Binds spliced mRNA upstream of exon-exon junctions (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nons [...] (484 aa)
     
 
  0.935
SMG7
Telomerase activating protein Est1; Plays multiple roles in growth and development. Involved in nonsense-mediated mRNA decay (NMD). May provide a link to the mRNA degradation machinery to initiate NMD and serve as an adapter for UPF proteins function. Required for meiotic progression through anaphase II of pollen mother cells. May counteract cyclin- dependent kinase (CDK) activity at the end of meiosis. May play a role in plant defense through its involvement in NMD (1059 aa)
         
0.922
AT1G15280
CASC3/Barentsz eIF4AIII binding (585 aa)
           
  0.922
PYM
Partner of Y14-MAGO (204 aa)
           
  0.922
LBA1
LOW-LEVEL BETA-AMYLASE 1; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding (1254 aa)
         
  0.910
PP2A-2
Protein phosphatase 2A-2 (306 aa)
         
  0.908
AT5G67510
60S ribosomal protein L26-2 (146 aa)
         
    0.900
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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