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ERF12 protein (Arabidopsis thaliana) - STRING interaction network
"ERF12" - Ethylene-responsive transcription factor 12 in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
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Gene Fusion
ERF12Ethylene-responsive transcription factor 12; Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis- related promoter element. Acts as a transcriptional inhibitor and may regulate other AtERFs (By similarity) (189 aa)    
Predicted Functional Partners:
Nudix hydrolase homolog 2; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives. In vitro, it can use both NADH and ADP- ribose as substrates; however the relevance of such substrates in vivo is unclear; Belongs to the Nudix hydrolase family (278 aa)
SBP (S-ribonuclease binding protein) family protein; Its function is described as zinc ion binding; Involved in biological_process unknown; Located in cellular_component unknown; Contains the following InterPro domains- Zinc finger, RING-type (InterPro-IPR001841), S-ribonuclease binding protein, SBP1, pollen (InterPro-IPR017066); BEST Arabidopsis thaliana protein match is- SBP (S-ribonuclease binding protein) family protein (TAIR-AT5G47050.1); Has 422 Blast hits to 421 proteins in 63 species- Archae - 0; Bacteria - 11; Metazoa - 35; Fungi - 13; Plants - 325; Viruses - 3; Other Eukaryot [...] (314 aa)
Exocyst subunit exo70 family protein E2; Influences the subcellular localization patterns of other exocyst complex proteins (e.g. SEC5A, SEC15A, SEC15B and EXO84B) leading to their recruitment to exocyst, well-defined large punctate structures throughout the cytosol. Essential component for the formation and the recruitment of exocyst subunits to the exocyst-positive organelle (EXPO), a secreted double membrane structure also called extracellular exosome, that acts as a sequester for cytosolic proteins to release them into the apoplast; Belongs to the EXO70 family (639 aa)
AP2-like ethylene-responsive transcription factor TOE2; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay (507 aa)
RESPONSE TO LOW SULFUR 1 (LSU1); BEST Arabidopsis thaliana protein match is- response to low sulfur 3 (TAIR-AT3G49570.1); Has 73 Blast hits to 73 proteins in 16 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 70; Viruses - 0; Other Eukaryotes - 3 (source- NCBI BLink) (94 aa)
Flowering-promoting factor 1-like protein 1; Encodes a small protein with unknown function and is similar to flower promoting factor 1. This gene is not expressed in apical meristem after floral induction but is expressed in roots, flowers, and in low abundance, leaves (181 aa)
Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin superfamily protein; Its function is described as lipid binding; Involved in lipid transport; Located in endomembrane system; Expressed in leaf whorl, sepal, flower, seed; Expressed during petal differentiation and expansion stage, E expanded cotyledon stage; Contains the following InterPro domains- Bifunctional inhibitor/plant lipid transfer protein/seed storage (InterPro-IPR016140), Plant lipid transfer protein/seed storage/trypsin-alpha amylase inhibitor (InterPro-IPR003612); BEST Arabidopsis thaliana protein matc [...] (91 aa)
LIM domain protein; Unknown protein; Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (948 aa)
GRAS family transcription factor family protein; Similar to a putative transcription factor and transcriptional coactivators. Repressor of GA responses and involved in gibberellic acid mediated signaling. Member of the DELLA proteins that restrain the cell proliferation and expansion that drives plant growth. The protein undergoes degradation in response to GA via the 26S proteasome. GAI may be involved in reducing ROS accumulation in response to stress by up-regulating the transcription of superoxide dismutases. Represses GA-induced vegetative growth and floral initiation. Rapidly deg [...] (533 aa)
DELLA protein RGL3; Probable transcriptional regulator that acts as a repressor of the gibberellin (GA) signaling pathway. No effect of the BOI proteins on its stability. Probably acts by participating in large multiprotein complexes that repress transcription of GA- inducible genes. Its activity may be regulated by phytohormones such as auxin and ethylene (By similarity); Belongs to the GRAS family. DELLA subfamily (523 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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