Groups of genes that are frequently observed in each other's genomic neighborhood.
Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
Genes that are sometimes fused into single open reading frames.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Pentatricopeptide repeat-containing protein At1g28690, mitochondrial; Tetratricopeptide repeat (TPR)-like superfamily protein; Contains the following InterPro domains- Pentatricopeptide repeat (InterPro-IPR002885); BEST Arabidopsis thaliana protein match is- Pentatricopeptide repeat (PPR) superfamily protein (TAIR-AT4G14820.1); Has 38334 Blast hits to 13612 proteins in 253 species- Archae - 1; Bacteria - 23; Metazoa - 125; Fungi - 112; Plants - 37440; Viruses - 0; Other Eukaryotes - 633 (source- NCBI BLink) (520 aa)
Predicted Functional Partners:
sucrose-6F-phosphate phosphohydrolase family protein; Catalyzes the final step of sucrose synthesis (425 aa)
Protein phosphatase 2C family protein; Encodes AHG1 (ABA-hypersensitive germination 1), a putative protein phosphatase 2C (PP2C). Expressed in seeds. AHG1 functions in seed development and germination (416 aa)
Your Current Organism:
NCBI taxonomy Id: 3702 Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress