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eIF4E3 protein (Arabidopsis thaliana) - STRING interaction network
"eIF4E3" - Translation initiation factor eIF-4E in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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eIF4E3Translation initiation factor eIF-4E; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome. Recognizes and binds the 7-methylguanosine- containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures (By similarity) (300 aa)    
Predicted Functional Partners:
eIFiso4G1
MIF4G domain and MA3 domain-containing protein; Plays a role in the accumulation of some potyvirus during viral infection (780 aa)
     
  0.994
EIF4G
Translation initiation factor eIF-4F; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5’-terminal secondary structure and recruitment of mRNA to the ribosome. Plays a role in the accumulation of some potyvirus during viral infection. Required for the accumulation of cucumber mosaic virus 3a protein and turnip crinkle virus p28 replication protein during viral infection. These proteins are necessary for cell-to-cell movement of the virus (1727 aa)
       
  0.974
AT4G30680
Initiation factor eIF-4 gamma, MA3 (263 aa)
     
  0.971
AT1G62410
MIF4G domain-containing protein (223 aa)
     
  0.971
ABH1
ABA HYPERSENSITIVE 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap str [...] (848 aa)
     
 
  0.947
PAB5
poly(A)-binding protein 5; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (682 aa)
     
  0.916
AT3G48830
Polynucleotide adenylyltransferase domain and RNA recognition motif-containing protein (881 aa)
     
  0.848
AT5G41690
RNA recognition motif-containing protein (567 aa)
     
  0.837
AT5G03580
RNA recognition motif-containing protein (101 aa)
     
  0.837
PAB2
poly(A) binding protein 2; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the cytoplasm, affects both translation and mRNA decay. Stimulates translation by interaction with translation initiation factor eIF4G, a subunit of the cap-binding complex eIF4F, bringing the 5’- and 3’-ends of the mRNA in proximity. The formation of this circular mRNP structure appears to be critical for the synergistic effects of the cap and the poly(A) tail in facilitating translation initiation, r [...] (629 aa)
     
  0.837
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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