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NRPA2 protein (Arabidopsis thaliana) - STRING interaction network
"NRPA2" - DNA-directed RNA polymerase I subunit 2 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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NRPA2DNA-directed RNA polymerase I subunit 2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and NRPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (1178 aa)    
Predicted Functional Partners:
NRPA1
DNA-directed RNA polymerase I subunit 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from NRPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of [...] (1670 aa)
 
  0.999
AT3G13940
DNA binding;DNA-directed RNA polymerases; Its function is described as DNA-directed RNA polymerase activity, DNA binding; Involved in transcription; Located in nucleus; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- RNA polymerase I associated factor, A49-like (InterPro-IPR009668); Has 222 Blast hits to 222 proteins in 107 species- Archae - 0; Bacteria - 2; Metazoa - 66; Fungi - 105; Plants - 33; Viruses - 0; Other Eukaryotes - 16 (source- NCBI BLink) (442 aa)
     
 
  0.999
NRPC1
DNA-directed RNA polymerase III subunit 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from NRPC1 and crosses the cleft near the catalytic site and is thought to promot [...] (1391 aa)
 
 
  0.999
ATRPAC42
ATRPAC42; Its function is described as DNA-directed RNA polymerase activity, protein dimerization activity, DNA binding; Involved in transcription; Located in nucleolus; Expressed in 19 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains- DNA-directed RNA polymerase, insert domain (InterPro-IPR011262), DNA-directed RNA polymerase, dimerisation (InterPro-IPR011261), DNA-directed RNA polymerase, RpoA/D/Rpb3-type (InterPro-IPR011263), DNA-directed RNA polymerase, RBP11-like (InterPro-IPR009025); BEST Arabidopsis thaliana protein match is- RNA polym [...] (375 aa)
   
 
  0.998
AT1G75670
Uncharacterized protein At1g75670; DNA-directed RNA polymerases; Its function is described as DNA-directed RNA polymerase activity; Involved in transcription; Located in cellular_component unknown; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- RNA polymerase Rpb7, N-terminal (InterPro-IPR005576); Has 35333 Blast hits to 34131 proteins in 2444 species- Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source- NCBI BLink) (196 aa)
     
 
  0.998
RPC14
RNA polymerase I(A) and III(C) 14 kDa subunit (139 aa)
     
 
  0.998
RPAC43
RNA polymerase I subunit 43 (RPAC43); Its function is described as DNA-directed RNA polymerase activity, protein dimerization activity, DNA binding; Involved in transcription; Expressed in 11 plant structures; Expressed during 4 anthesis, C globular stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; Contains the following InterPro domains- DNA-directed RNA polymerase, insert domain (InterPro-IPR011262), DNA-directed RNA polymerase, dimerisation (InterPro-IPR011261), DNA-directed RNA polymerase, RpoA/D/Rpb3-type (InterPro-IPR011263), DNA-dir [...] (385 aa)
   
 
  0.997
NRPD1B
DNA-directed RNA polymerase V subunit 1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase V involved in RNA-directed DNA methylation-dependent (RdDM) silencing of endogenous repeated sequences, including transposable elements. Also required for full erasure of methylation when the RNA trigger is withdrawn. Seems also involved in the synthesis of short-interfering RNAs (siRNA). Essential component of a self- reinforcing loop coupling de novo DNA methylatio [...] (1976 aa)
   
 
  0.995
NRPB5
Eukaryotic rpb5 RNA polymerase subunit family protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. Component of RNA polymerase IV which mediates short- interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (R [...] (205 aa)
   
  0.995
AT3G11964
rRNA biogenesis protein RRP5; Involved in the biogenesis of ribosomal RNA (rRNA). Required for the formation of 5.8S rRNA. Required for normal development of female gametophytes (1896 aa)
     
 
  0.995
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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