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NCED5 protein (Arabidopsis thaliana) - STRING interaction network
"NCED5" - Probable 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic in Arabidopsis thaliana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
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Gene Fusion
NCED5Probable 9-cis-epoxycarotenoid dioxygenase NCED5, chloroplastic; Encodes 9-cis-epoxycarotenoid dioxygenase, a key enzyme in the biosynthesis of abscisic acid. The expression of this gene increases during the first 6h of imbibition (589 aa)    
Predicted Functional Partners:
NAD(P)-binding Rossmann-fold superfamily protein; Encodes a cytosolic short-chain dehydrogenase/reductase involved in the conversion of xanthoxin to ABA-aldehyde during ABA biosynthesis. Mutants are insensitive to sucrose and glucose (285 aa)
Abscisic aldehyde oxidase 3; In higher plants aldehyde oxidases (AO) appear to be homo- and heterodimeric assemblies of AO subunits with probably different physiological functions. AO-delta seems to be involved in the last step of abscisic acid biosynthesis, at least in leaves and seeds. In vitro, AO-delta oxidizes abscisic aldehyde to abscisic acid (ABA). In vitro, AO-delta also uses indole-3- aldehyde (IAld), benzaldehyde, 1-naphthaldehyde and cinnamaldehyde as substrate; the AAO2-AAO3 dimer also uses abscisic aldehyde as substrate (1332 aa)
Zeaxanthin epoxidase, chloroplastic; Zeaxanthin epoxidase that plays an important role in the xanthophyll cycle and abscisic acid (ABA) biosynthesis. Converts zeaxanthin into antheraxanthin and subsequently violaxanthin. Required for resistance to osmotic and drought stresses, ABA- dependent stomatal closure, seed development and dormancy, modulation of defense gene expression and disease resistance and non-photochemical quencing (NPQ). Through its role in ABA biosynthesis, regulates the expression of stress-responsive genes such as RD29A during osmotic stress and is required for norma [...] (667 aa)
Auxin response factor 10; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5’-TGTCTC-3’ found in the auxin-responsive promoter elements (AuxREs). Could act as transcriptional activator or repressor. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression (693 aa)
Encodes a 85.9 kDa protein containing novel repeats and zinc fingers described as protein interaction domains. VAR3 is a part of a protein complex required for normal chloroplast and palisade cell development. Mutants display a variegated phenotype due to somatic areas lacking or containing developmentally retarded chloroplasts and greatly reduced numbers of palisade cells (758 aa)
Zeta-carotene desaturase, chloroplastic/chromoplastic; Plays a crucial role in plant growth and development. Is essential for the biosynthesis of carotenoids. Carotenoids are involved in different physiological processes, including coloration, photoprotection, biosynthesis of abscisic acid (ABA) and chloroplast biogenesis. Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7’. Shows stereoselectivity toward trans C15-C15’zeta-carotene double bond. [...] (558 aa)
Cytochrome P450, family 707, subfamily A, polypeptide 2; Encodes a protein with ABA 8’-hydroxylase activity, involved in ABA catabolism. Member of the CYP707A gene family. This gene predominantly accumulates in dry seeds and is up-regulated immediately following imbibition. CYP707A2 appears to play a major role in the rapid decrease in ABA levels during early seed imbibition (482 aa)
Cytochrome P450, family 707, subfamily A, polypeptide 1; Encodes a protein with ABA 8’-hydroxylase activity, involved in ABA catabolism. Member of the CYP707A gene family. CYP707A1 appears to play an important role in determining the ABA levels in dry seeds. Gene involved in postgermination growth. Overexpression of CYP707A1 leads to a decrease in ABA levels and a reduction in after-ripening period to break dormancy (484 aa)
Phytoene synthase, chloroplastic; Catalyzes the reaction from prephytoene diphosphate to phytoene; Belongs to the phytoene/squalene synthase family (437 aa)
15-cis-zeta-carotene isomerase, chloroplastic; Isomerase involved in the biosynthesis of carotenoids. Catalyzes the cis- to trans-conversion of the 15-cis-bond in 9,15,9’-tri-cis-zeta-carotene (367 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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