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JAZ8 protein (Arabidopsis thaliana) - STRING interaction network
"JAZ8" - Jasmonate-zim-domain protein 8 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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JAZ8Jasmonate-zim-domain protein 8; Repressor of jasmonate responses. Unable to associate strongly with COI1 in the presence of jasmonoyl-isoleucine (JA- Ile) and is therefore more resistant to JA-medisted-degradation than other TIFY/JAZ proteins. Repress gene expression through direct recruitment of the corepressor TOPLESS to cognate transcription factors (131 aa)    
Predicted Functional Partners:
JAZ1
JAZ1 is a nuclear-localized protein involved in jasmonate signaling. JAZ1 transcript levels rise in response to a jasmonate stimulus. JAZ1 can interact with the COI1 F-box subunit of an SCF E3 ubiquitin ligase in a yeast-two-hybrid assay only in the presence of jasmonate-isoleucine (JA-ILE) or coronatine. Application of jasmonate methyl ester to Arabidopsis roots reduces the levels of a JAZ1-GUS fusion protein, presumably by stimulating ubiquitin-proteasome-mediated degradation. The Jas domain appears to be important for JAZ1-COI1 interactions in the presence of coronatine. Two positi [...] (253 aa)
     
 
  0.990
JAZ5
Jasmonate-zim-domain protein 5; Repressor of jasmonate responses (274 aa)
     
 
  0.974
JAZ10
Jasmonate-zim-domain protein 10; Modulator of growth inhibition. Isoform 2 and isoform 3, but not isoform 1, confer a strong methyl-jasmonate insensitivity. Not involved in the growth response to salicylic acid or indole-3- acetic acid. Isoform 3 acts as an endogenous repressor of JA signal output in JA-stimulated cells (197 aa)
     
 
  0.971
JAZ6
Jasmonate-zim-domain protein 6; JAZ6 transcript levels rise in response to a jasmonate stimulus and a GFP-JAZ6 fusion protein localizes to the nucleus. Application of jasmonate methyl ester to Arabidopsis roots reduces the levels of a JAZ6-GUS fusion protein, presumably by stimulating ubiquitin-proteasome-mediated degradation (269 aa)
     
 
  0.962
TIFY10B
TIFY domain/Divergent CCT motif family protein; Repressor of jasmonate responses. Jasmonoyl-isoleucine (JA-Ile) specifically promotes COI1-TIFY10B/JAZ2 interaction. Activated by MYC2, MYC3 and MYC4 transcription factors; Belongs to the TIFY/JAZ family (249 aa)
     
 
  0.949
MYC2
Basic helix-loop-helix (bHLH) DNA-binding family protein; Transcriptional activator. Common transcription factor of light, abscisic acid (ABA), and jasmonic acid (JA) signaling pathways. With MYC3 and MYC4, controls additively subsets of JA- dependent responses. In cooperation with MYB2 is involved in the regulation of ABA-inducible genes under drought stress conditions. Can form complexes with all known glucosinolate-related MYBs to regulate glucosinolate biosynthesis. Binds to the MYC recognition site (5’-CACATG-3’), and to the G-box (5’-CACNTG-3’) and Z-box (5’-ATACGTGT-3’) of promo [...] (623 aa)
     
 
  0.946
TIFY7
TIFY domain/Divergent CCT motif family protein; JAZ9 is a protein presumed to be involved in jasmonate signaling. JAZ9 transcript levels rise in response to a jasmonate stimulus. JAZ9 can interact with the COI1 F-box subunit of an SCF E3 ubiquitin ligase in a yeast-two-hybrid assay only in the presence of jasmonate-isoleucine (JA-ILE) or coronatine. The Jas domain appears to be important for JAZ9-COI1 interactions in the presence of coronatine. Two positive residues (R205 and R206) in the Jas domain shown to be important for coronatine -dependent COI1 binding are not required for bindi [...] (267 aa)
     
 
  0.940
JAZ12
Jasmonate-zim-domain protein 12; Repressor of jasmonate responses (187 aa)
     
 
  0.935
NINJA
Novel interactor of JAZ; Acts as a transcriptional repressor. Negative regulator of jasmonate responses. Connects the JAZ proteins and the non-JAZ protein TIFY8 with the TOPLESS corepressors; Belongs to the Ninja family (425 aa)
       
 
  0.925
JAZ3
Jasmonate-zim-domain protein 3; JAZs are direct targets of the SCFCOI1 E3 ubiquitin-ligase and JA treatment induces their proteasome-mediated degradation. Furthermore, JAI3 negatively regulates the key transcriptional activator of JA responses, AtMYC2. The C-terminal portion of JAZ3, including the Jas domain, appears to be important for JAZ3-COI1 binding in the presence of coronatine; Belongs to the TIFY/JAZ family (352 aa)
     
 
  0.923
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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