STRINGSTRING
ERD4 protein (Arabidopsis thaliana) - STRING interaction network
"ERD4" - Early-responsive to dehydration 4 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERD4Early-responsive to dehydration 4; Acts as an osmosensitive calcium-permeable cation channel (724 aa)    
Predicted Functional Partners:
RIN4
RPM1 interacting protein 4; Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its associ [...] (211 aa)
       
 
  0.691
ERD3
Putative methyltransferase PMT21 (600 aa)
           
  0.637
ERD7
EARLY-RESPONSIVE TO DEHYDRATION 7 (452 aa)
     
   
  0.595
SMU1
SUPPRESSORS OF MEC-8 AND UNC-52 1; Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development. Required for proper accumulation of SMU2 (511 aa)
           
  0.555
AT4G36750
Quinone reductase family protein; Catalyzes the transfer of electrons from NADH and NADPH to reduce quinone to the hydroquinone state (273 aa)
           
  0.554
SNF7.1
SNF7 family protein; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity) (219 aa)
       
      0.489
SKD1
SUPPRESSOR OF K+ TRANSPORT GROWTH DEFECT1; Involved in the transport of biosynthetic membrane proteins from the prevacuolar/endosomal compartment to the vacuole. Required for multivesicular body (MVB) protein sorting. Catalyzes the ATP-dependent dissociation of class E VPS proteins from endosomal membranes, such as the disassembly of the ESCRT-III complex (PubMed-17468262, PubMed-20663085, PubMed-21810997, PubMed-22258747, PubMed-24812106). May also regulate cell cycle (PubMed-20663085). Required during seed development for the formation of mucilage in seed coat and testa (PubMed-20930 [...] (435 aa)
       
      0.489
SNF7.2
SNF7 family protein; Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-III complex is probably involved in the concentration of MVB cargo (By similarity) (213 aa)
       
      0.489
AT1G08270
Uncharacterized protein (132 aa)
       
      0.489
AT1G28590
GDSL esterase/lipase (403 aa)
           
  0.477
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]