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IMD3 protein (Arabidopsis thaliana) - STRING interaction network
"IMD3" - Isopropylmalate dehydrogenase 3 in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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IMD3Isopropylmalate dehydrogenase 3; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (404 aa)    
Predicted Functional Partners:
IIL1
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (509 aa)
 
  0.999
IPMI2
Isopropylmalate isomerase 2; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. Functions redundantly with LEUD2 in aliphatic glucosinolate biosynthesis (256 aa)
 
  0.999
IPMI1
Isopropylmalate isomerase 1; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. Functions redundantly with LEUD1 in aliphatic glucosinolate biosynthesis (253 aa)
 
  0.999
AT2G43090
Aconitase/3-isopropylmalate dehydratase protein; Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate. plays an essential role in leucine biosynthesis and female gametophyte development (251 aa)
 
  0.996
CSR1
Acetolactate synthase; Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis (670 aa)
 
  0.990
BCAT3
Branched-chain aminotransferase 3; Converts 2-oxo acids to branched-chain amino acids. Acts on leucine, isoleucine and valine. Also involved in methionine chain elongation cycle of aliphatic glucosinolate formation. Catalyzes the conversion of 5-methylthiopentyl-2-oxo and 6- methylthiohexyl-2-oxo acids to their respective Met derivatives, homomethionine and dihomo-methionine, respectively (413 aa)
   
 
  0.989
BCAT4
Branched-chain aminotransferase4; Converts 2-oxo acids to branched-chain amino acids. Shows activity with L-Leu, L-Ile and L-Val as amino donors and alpha-keto-glutarate as an amino acceptor, but no activity for D- isomers of Leu, Ile, Val, Asp, Glu or Ala. Acts on methionine and its derivatives and the corresponding 2-oxo acids. Catalyzes the initial deamination of methionine to 4-methylthio-2-oxobutyrate as well as the transamination of other typical intermediates of the methionine chain elongation pathway (354 aa)
   
 
  0.989
VAT1
VALINE-TOLERANT 1; Regulatory subunit of acetohydroxy-acid synthase. Involved in the feed-back inhibition by branched-chain amino acids but not in herbicide tolerance (477 aa)
 
 
  0.989
MAM1
Methylthioalkylmalate synthase 1; Determines the side chain length of aliphatic glucosinolate structures. Catalyzes exclusively the condensation reactions of both the first and second methionine carbon chain elongation (506 aa)
 
  0.987
AT2G31810
ACT domain-containing small subunit of acetolactate synthase protein; Regulatory subunit of acetohydroxy-acid synthase. Involved in the feed-back inhibition by branched-chain amino acids. Contains 2 repeats, each of them being able to activate partially the catalytic subunit. The enzyme reconstituted with the first repeat is inhibited by leucine, but not by valine or isoleucine and the enzyme reconstituted with the second repeat is not inhibited by any branched-chain amino acid (491 aa)
 
 
  0.986
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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