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IMPL1 protein (Arabidopsis thaliana) - STRING interaction network
"IMPL1" - Myo-inositol monophosphatase like 1 in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
IMPL1Myo-inositol monophosphatase like 1; Phosphatase acting preferentially on D-myoinositol 1- phosphate (D-Ins 1-P) (371 aa)    
Predicted Functional Partners:
MIPS3
Myo-inositol-1-phosphate synthase; Involved in myo-inositol synthesis (510 aa)
       
  0.981
MIPS1
D-myo-Inositol 3-Phosphate Synthase 1; Catalyzes the majority of myo-inositol synthesis required for plant growth and development. Acts as a repressor of programmed cell death and protects plant cells against cell death under high light intensity or long days. Controls its own transcription by inhibiting ATXR6 activity. Reduces the deposition of inhibitory histone marks on its own promoter (511 aa)
       
  0.969
MIPS2
Myo-inositol-1-phosphate synthase 2; Involved in myo-inositol synthesis (510 aa)
       
  0.969
SAL2
SAL2 phosphatase; Converts adenosine 3’-phosphate 5’-phosphosulfate (PAPS) to adenosine 5’-phosphosulfate (APS) and 3’(2’)-phosphoadenosine 5’- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS (By similarity). Prevents both the toxicity of PAP on RNA processing enzymes as well as the product inhibition by PAP of sulfate conjugation. Is also able to hydrolyze inositol 1,4-bisphosphate (347 aa)
     
 
  0.943
IMPL2
Phosphatase IMPL2; Phosphatase required for histidine production. Acts also on L-galactose 1-phosphate (L-Gal 1-P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1-phosphate (D-Ins 1-P) (375 aa)
   
   
0.941
AT-HF
HIS HF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutamine amidotransferase domain provides the ammonia necessary to the cyclase domain to produce IGP and AICAR from PRFAR (592 aa)
   
 
  0.936
PIS2
Probable CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (By similarity) (225 aa)
       
  0.935
PIS1
Phosphatidylinositol synthase 1; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme (227 aa)
       
  0.935
VTC4
Inositol-phosphate phosphatase; Phosphatase acting on L-galactose 1-phosphate (L-Gal 1- P), D-myoinositol 3-phosphate (D-Ins 3-P) and D-myoinositol 1- phosphate (D-Ins 1-P). Can also use beta-glycerophosphate (glycerol 2-P) and, to a leser extend, D-galactose 1-phosphate (D- Gal 1-P), alpha-D-glucose 1-phosphate (a-D-Glc 1-P), D-manitol 1- phosphate and adenosine 2’-monophosphate as substrates. No activity with D-fructose 1-phosphate (D-Fru 1-P), fructose 1,6- bisphosphate (Fru 1,6-bisP), D-glucose 6-phosphate (D-Glc 6-P), D- alpha-glycerophosphate (glycerol 3-P), D-sorbitol 6-phosphat [...] (271 aa)
   
 
0.929
SAL1
Inositol polyphosphate 1-phosphatase; Converts adenosine 3’-phosphate 5’-phosphosulfate (PAPS) to adenosine 5’-phosphosulfate (APS) and 3’(2’)-phosphoadenosine 5’- phosphate (PAP) to AMP. May regulate the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS. May play a role in the biosynthesis of sulfate conjugates and RNA processing. Is also able to hydrolyze inositol 1,4-bisphosphate and inositol 1,3,4-trisphosphate. Could be considered as a negative regulator of abscisic acid (ABA)- and stress-responsive genes, through modulating the inositol 1,4,5-trisphosphate [...] (407 aa)
     
 
0.926
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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