STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G31550GDSL-like Lipase/Acylhydrolase superfamily protein; Its function is described as lipase activity, hydrolase activity, acting on ester bonds, carboxylesterase activity; Involved in lipid metabolic process; Located in vacuole; Expressed in 20 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Lipase, GDSL (InterPro:IPR001087); BEST Arabidopsis thaliana protein match is: GDSL-like Lipase/Acylhydrolase superfamily protein (TAIR:AT1G28600.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fung [...] (394 aa)    
Predicted Functional Partners:
AT5G49220
Protein of unknown function (DUF789); Contains the following InterPro domains: Protein of unknown function DUF789 (InterPro:IPR008507); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF789) (TAIR:AT4G16100.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink)
      
 0.869
AT5G46510
Disease resistance protein (TIR-NBS-LRR class) family; Its function is described as transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; Involved in signal transduction, defense response, apoptosis, innate immune response; Located in intrinsic to membrane; Expressed in 21 plant structures; Expressed during 12 growth stages; Contains the following InterPro domains: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST [...]
      
 0.840
AT5G46490
Disease resistance protein (TIR-NBS-LRR class) family; Its function is described as transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; Involved in signal transduction, apoptosis, defense response, innate immune response; Located in intrinsic to membrane; Contains the following InterPro domains: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (T [...]
      
 0.832
AT5G46260
Disease resistance protein (TIR-NBS-LRR class) family; Its function is described as transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; Involved in signal transduction, defense response, apoptosis, innate immune response; Located in intrinsic to membrane; Contains the following InterPro domains: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767); BEST Arabidopsis thaliana protein match is: Disease resistance protein (T [...]
   
  
 0.797
AT5G46270
Disease resistance protein (TIR-NBS-LRR class) family; Its function is described as transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; Involved in signal transduction, apoptosis, defense response, innate immune response; Located in intrinsic to membrane; Expressed in 17 plant structures; Expressed during 10 growth stages; Contains the following InterPro domains: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Disease resistance protein (InterPro:IPR000767), Toll-Interleukin receptor (InterPro:IPR000157); BEST [...]
   
  
 0.711
AT1G65850
Disease resistance protein (TIR-NBS-LRR class) family; Its function is described as transmembrane receptor activity, ATP binding; Involved in signal transduction, apoptosis, defense response, innate immune response; Located in intrinsic to membrane; Expressed in 8 plant structures; Expressed during LP.04 four leaves visible, 4 anthesis, LP.02 two leaves visible, petal differentiation and expansion stage, D bilateral stage; Contains the following InterPro domains: NB-ARC (InterPro:IPR002182), Toll-Interleukin receptor (InterPro:IPR000157), Disease resistance protein (InterPro:IPR000767) [...]
      
 0.697
RPP8
Disease resistance protein (CC-NBS-LRR class) family; Disease resistance protein. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. The interaction with TIP (TCV-interacting protein) may be essential for the recognition of the avirulence proteins, and the triggering of the defense response. Triggers resistance to turnip crinkle virus (TCV) via a SAG101-dependent pathway; Be [...]
   
  
 0.690
CW9
Disease resistance protein (CC-NBS-LRR class) family; Probable disease resistance protein
   
  
 0.657
AT1G58848
Disease resistance protein (CC-NBS-LRR class) family; Potential disease resistance protein
      
 0.641
AT1G59218.1
Disease resistance protein (CC-NBS-LRR class) family; Potential disease resistance protein
      
 0.641
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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