STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G31780Uncharacterized protein At1g31780; Contains the following InterPro domains: Conserved oligomeric complex COG6 (InterPro:IPR010490); Has 384 Blast hits to 379 proteins in 190 species: Archae - 0; Bacteria - 4; Metazoa - 151; Fungi - 156; Plants - 42; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink) (680 aa)    
Predicted Functional Partners:
AT1G67930
Golgi transport complex protein-related; Located in chloroplast; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Conserved oligomeric Golgi complex, subunit 5 (InterPro:IPR019465); Has 4471 Blast hits to 590 proteins in 146 species: Archae - 0; Bacteria - 79; Metazoa - 393; Fungi - 221; Plants - 65; Viruses - 7; Other Eukaryotes - 3706 (source: NCBI BLink)
   
 0.999
AT1G73430
Sec34-like family protein; Its function is described as molecular_function unknown; Involved in intracellular protein transport; Located in chloroplast, membrane, cis-Golgi network; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Sec34-like protein (InterPro:IPR007265); Has 353 Blast hits to 340 proteins in 172 species: Archae - 0; Bacteria - 4; Metazoa - 117; Fungi - 139; Plants - 43; Viruses - 0; Other Eukaryotes - 50 (source: NCBI BLink)
   
 0.999
AT4G01400
Conserved oligomeric Golgi complex subunit 4; Required for normal Golgi function
   
 0.999
AT4G24840
Oligomeric golgi complex subunit-like protein; Its function is described as molecular_function unknown; Involved in protein transport, Golgi organization; Located in vacuole; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: COG complex component, COG2 (InterPro:IPR009316); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink)
   
 0.999
AT5G11980
Conserved oligomeric Golgi complex component-related / COG complex component-related; Contains the following InterPro domains: Conserved oligomeric Golgi complex, subunit 8 (InterPro:IPR016632), Dor1-like protein (InterPro:IPR007255); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink); Belongs to the COG8 family
   
 0.999
AT5G16300
Vps51/Vps67 family (components of vesicular transport) protein; Contains the following InterPro domains: Vps51/Vps67 (InterPro:IPR014812); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink)
   
 0.999
EYE
Conserved oligomeric golgi complex component-related / cog complex component-like protein; Encodes a protein that is homologous to Cog7, a subunit of the conserved oligomeric Golgi (COG) complex, which is required for the normal morphology and function of the Golgi apparatus. It is likely to be involved in transport or retention of Golgi-localized proteins and in maintenance of Golgi morphology
   
 0.999
AT1G79990
Coatomer subunit beta'-1; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity); Belongs to the WD repeat COPB2 family
   
  0.989
AT4G34450
Coatomer gamma-2 subunit, putative / gamma-2 coat protein, putative / gamma-2 COP, putative; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non- clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity)
   
 0.967
VPS54
Vacuolar protein sorting-associated protein 54; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex facilitates tethering as well as SNARE complex assembly at the Golgi (By similarity). Probably involved in pollen tube elongation and other polar growth
   
 
 0.963
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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