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FRL2 protein (Arabidopsis thaliana) - STRING interaction network
"FRL2" - Inactive FRIGIDA-like protein 2 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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FRL2Inactive FRIGIDA-like protein 2; Family member of FRI-related genes that is required for the winter-annual habit. Genbank accession BK004885; Belongs to the Frigida family (473 aa)    
Predicted Functional Partners:
FES1
Zinc finger C-x8-C-x5-C-x3-H type family protein; Transcriptional activator involved in the FRIGIDA- mediated vernalization pathway, but not in the autonomous flowering pathway. Acts cooperatively with FRI (FRIGIDA) or FRL1 (FRIGIDA-LIKE 1) to promote FLC (FLOWERING LOCUS C) expression. Required for the stabilization of the FRI-C complex (587 aa)
           
  0.767
SUF4
Zinc finger (C2H2 type) family protein; Encodes SUF4 (SUPPRESSOR of FRI 4), a putative zinc-finger-containing transcription factor that is required for delayed flowering in winter-annual Arabidopsis. suf4 mutations strongly suppress the late-flowering phenotype of FRI (FRIGIDA) mutants. suf4 mutants also show reduced H3K4 trimethylation at FLC (FLOWERING LOCUS C), a floral inhibitor. SUF4 may act to specifically recruit a putative histone H3 methyltransferase EFS (EARLY FLOWERING IN SHORT DAYS) and the PAF1-like complex to the FLC locus (367 aa)
           
  0.766
RAP2.7
Ethylene-responsive transcription factor RAP2-7; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay; Belongs to the AP2/ERF transcription factor family. AP2 subfamily (464 aa)
           
  0.673
AT5G61920
Protein FLX-like 4; Involved in FLC activation and flowering time control, but has no transcriptional activation activity. Probably part of the FRI-C complex, but is not redundant with FLX (238 aa)
           
  0.625
AP2
Integrase-type DNA-binding superfamily protein; Probable transcriptional activator that promotes early floral meristem identity. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Plays a central role in the specification of floral identity, particularly for the normal development of sepals and petals in the wild-type flower, by spatially controlling the expression domains of multiple floral organ identity genes. Acts as A class cadastral protein by repressing the C class floral homeotic gene AGAMOUS in association with other repressors lik [...] (432 aa)
           
  0.585
TOE3
AP2-like ethylene-responsive transcription factor TOE3; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). May regulate negatively the transition to flowering time and confers flowering time delay; Belongs to the AP2/ERF transcription factor family. AP2 subfamily (352 aa)
           
  0.582
ARR3
Two-component response regulator ARR3; Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling (231 aa)
           
  0.534
LATE
C2H2-like zinc finger protein; Acts as a transcriptional repressor. Prevents the photoperiodic and circadian clock-dependent transition to flowering in long days (LD) by repressing the expression of flowering time genes (e.g. FT, GI and CO) in the leaf vasculature, and by interfering with floral meristem identity genes at the apex (e.g. SOC1 and LFY) (173 aa)
           
  0.534
HUA2
Tudor/PWWP/MBT domain-containing protein; Transcription factor that functions as repressor of flowering by enhancing the expression of several genes that delay flowering including FLC, FLM/MAF1, MAF2 and SVP. Also acts in the floral homeotic AGAMOUS (AG) pathway, specifically by processing the AGAMOUS pre-mRNA. Functions in association with HUA1 and HEN4 in AG pre-mRNA processing. Involved in all three aspects of the AG functions, the specification of stamen and carpel identities, the control of floral determinacy, and the spatial restriction of AP1 expression. Acts as transcription re [...] (1392 aa)
           
  0.529
MAF1
K-box region and MADS-box transcription factor family protein; MADS domain protein - flowering regulator that is closely related to FLC. Deletion of this locus in Nd ecotype is correlated with earlier flowering in short days suggesting function as a negative regulator of flowering (196 aa)
           
  0.529
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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