Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
POLYAMINE UPTAKE TRANSPORTER 2; Probable cell membrane polyamine/proton symporter involved in the polyamine uptake in cells (495 aa)
Predicted Functional Partners:
Aspartate kinase-homoserine dehydrogenase ii (916 aa)
Aspartate kinase-homoserine dehydrogenase i (911 aa)
transducin/WD-40 repeat-containing protein (392 aa)
Gamma-glutamyl phosphate reductase; P5CS plays a key role in proline biosynthesis, leading to osmoregulation in plants (726 aa)
Proline transporter 3; Proline transporter that mediates proline and glycine betaine transport. When expressed in a heterologous system (yeast), imports L-proline, glycine betaine and GABA across the plasma membrane (436 aa)
Pyrroline-5-carboxylate reductase (276 aa)
Carbonic anhydrase; Reversible hydration of carbon dioxide (217 aa)
Cationic amino acid transporter 8; Permease involved in the transport of the cationic neutral or acidic amino acids (590 aa)