• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
BRX protein (Arabidopsis thaliana) - STRING interaction network
"BRX" - DZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRXDZC (Disease resistance/zinc finger/chromosome condensation-like region) domain containing protein; Belongs to five-member BRX gene family. Arabidopsis BRX genes share high levels of similarity among each others, with several conserved domains. The most distinct is BRX domain - highly conserved in all BRX genes among distantly related species. This protein-protein interaction domain is required and sufficient for BRX activity. BRX encodes a key regulator of cell proliferation and elongation in the root, which has been implicated in the brassinosteroid (BR) pathway as well as regulation [...] (344 aa)    
Predicted Functional Partners:
MP
Transcriptional factor B3 family protein / auxin-responsive factor AUX/IAA-related; Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5’-TGTCTC-3’ found in the auxin-responsive promoter elements (AuxREs). Seems to act as transcriptional activator. Formation of heterodimers with Aux/IAA proteins may alter their ability to modulate early auxin response genes expression. Mediates embryo axis formation and vascular tissues differentiation. Functionally redundant with ARF7. May be necessary to counteract AMP1 activity (902 aa)
       
 
  0.942
CLE45
CLAVATA3/ESR (CLE)-related protein 45; Belongs to a large gene family, called CLE for CLAVATA3/ESR-related, encoding small peptides with conserved carboxyl termini (124 aa)
           
  0.903
OPS
UPF0503 protein At3g09070, chloroplastic; Protein of unknown function (DUF740); Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in plasma membrane; Expressed in 17 plant structures; Expressed during 8 growth stages; Contains the following InterPro domains- Protein of unknown function DUF740 (InterPro-IPR008004); BEST Arabidopsis thaliana protein match is- Protein of unknown function (DUF740) (TAIR-AT5G01170.1); Has 844 Blast hits to 758 proteins in 136 species- Archae - 0; Bacteria - 50; Metazoa - 319; Fungi - 62; Plants - 144; V [...] (685 aa)
           
  0.838
BAM3
Leucine-rich repeat receptor-like serine/threonine-protein kinase BAM3; Encodes a CLAVATA1-related receptor kinase-like protein required for both shoot and flower meristem function. It has a broad expression pattern and is involved in vascular strand development in the leaf, control of leaf shape, size and symmetry, male gametophyte development and ovule specification and function (992 aa)
           
  0.813
TOE2
AP2-like ethylene-responsive transcription factor TOE2; Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). Regulates negatively the transition to flowering time and confers flowering time delay (507 aa)
       
      0.762
AT5G22310
Unknown protein; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT3G11590.1); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (481 aa)
       
      0.762
AT3G28715
ATPase, V0/A0 complex, subunit C/D; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system; Belongs to the V-ATPase V0D/AC39 subunit family (351 aa)
       
      0.762
AT1G49850
Probable E3 ubiquitin-protein ligase RHY1A; Probable E3 ubiquitin-protein ligase that may possess E3 ubiquitin ligase activity in vitro (250 aa)
       
      0.762
AT1G01440
Protein of unknown function (DUF3133); Contains the following InterPro domains- Protein of unknown function DUF3133 (InterPro-IPR021480); BEST Arabidopsis thaliana protein match is- Protein of unknown function (DUF3133) (TAIR-AT4G01090.1); Has 702 Blast hits to 662 proteins in 107 species- Archae - 0; Bacteria - 15; Metazoa - 235; Fungi - 59; Plants - 328; Viruses - 0; Other Eukaryotes - 65 (source- NCBI BLink) (664 aa)
       
      0.762
CIPK9
CBL-interacting serine/threonine-protein kinase 9; CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium- dependent manner. Involved in K(+) homeostasis under low-K(+) stress; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily (451 aa)
       
      0.762
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (11%) [HD]