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AT1G31910 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G31910" - Phosphomevalonate kinase, peroxisomal in Arabidopsis thaliana
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Predicted Interactions
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Gene Fusion
AT1G31910Phosphomevalonate kinase, peroxisomal; GHMP kinase family protein; Its function is described as kinase activity, ATP binding; Involved in phosphorylation; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Phosphomevalonate kinase, eukaryotic (InterPro-IPR005916), Phosphomevalonate kinase, ERG8 (InterPro-IPR016005), Ribosomal protein S5 domain 2-type fold (InterPro-IPR020568), GHMP kinase (InterPro-IPR006204), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro-IPR014721), GHMP kinase, C-terminal (InterPro-IPR013750); [...] (505 aa)    
Predicted Functional Partners:
Encodes a protein with mevalonate kinase activity involved in the mevalonate pathway; Belongs to the GHMP kinase family. Mevalonate kinase subfamily (378 aa)
Diphosphomevalonate decarboxylase MVD1, peroxisomal; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Is specific for (R)-5- diphosphomevalonate (MVAPP). The catalytic efficiency with (R)-5- phosphomevalonate (MVAP) as substrate is 10000-fold lower than for MVAPP. Can complement a yeast mutant defective in MVD activity (412 aa)
Diphosphomevalonate decarboxylase MVD2, peroxisomal; Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids. Is specific for (R)-5-diphosphomevalonate (MVAPP). The catalytic efficiency with (R)-5-phosphomevalonate (MVAP) as substrate is 10000-fold lower than for MVAPP; Belongs to the diphosphomevalonate decarboxylase family (419 aa)
Hydroxymethylglutaryl-CoA synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Devoided of acetoacetyl-CoA thiolase (AACT) activity. Required for the development of both tapetosomes and elaioplasts in tapetal cells and for pollen viability during pollen tube elongation (461 aa)
Pre-mRNA-processing protein 40C; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. The Mediator complex, having a compact conformation in its free form, is recruited to promoters by direct interactions with regulatory proteins and serves for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. I [...] (835 aa)
Isopentenyl-diphosphate Delta-isomerase I, chloroplastic; Encodes a protein with isopentenyl diphosphate-dimethylallyl diphosphate isomerase activity. There is genetic evidence that it functions in the mevalonate, but not the MEP biosynthetic pathway; Belongs to the IPP isomerase type 1 family (291 aa)
Encodes a 3-hydroxy-3-methylglutaryl coenzyme A reductase, which is involved in melavonate biosynthesis and performs the first committed step in isoprenoid biosynthesis. Expression is activated in dark in leaf tissue but not controlled by light in the root (confine (642 aa)
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic; Enzyme of the plastid non-mevalonate pathway for isoprenoid biosynthesis that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP). Is essential for chloroplast development and required for pigments and gibberellins biosynthesis (302 aa)
1-Deoxy-d-xylulose 5-phosphate reductoisomerase (DXR) catalyzes the first committed step of the 2-C-methyl-d-erythritol 4-phosphate pathway for isoprenoid biosynthesis. In Arabidopsis, DXR is encoded by a single-copy gene. Arabidopsis DXR is targeted to plastids and localizes into chloroplasts of leaf cells. DXR knockout or strongly silenced lines have a seedling lethal, albino phenotype. Transgenic, partially silenced lines expressing 35S-DXR have a variegated phenotype (497 aa)
Encodes squalene synthase, which converts two molecules of farnesyl diphosphate (FPP) into squalene via an intermediate- presqualene diphosphate (PSPP). It is generally thought to be one of the key enzymes of sterol biosynthesis, since it catalyzes the first pathway-specific reaction of the sterol branch of the isoprenoid pathway (410 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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