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NAC012 protein (Arabidopsis thaliana) - STRING interaction network
"NAC012" - NAC domain containing protein 12 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NAC012NAC domain containing protein 12; Transcriptional activator of genes involved in biosynthesis of secondary walls. Together with NST1, required for the secondary cell wall thickening and lignification of sclerenchymatous fibers and secondary xylem vessels (tracheary elements). Seems to repress the secondary cell wall thickening of xylary fibers. May also regulate the secondary cell wall lignification of other tissues. Binds to and activates the promoter of MYB46 (358 aa)    
Predicted Functional Partners:
MYB46
Myb domain protein 46; Transcription activator. Involved in the regulation of secondary wall biosynthesis in fibers and vessels (PubMed-17890373). Transcription activator of the mannan synthase CSLA9 that recognizes and binds to the DNA consensus sequence 5’- [AG][GT]T[AT]GGT[GA]-3’ cis-regulatory element of CSLA9 promoter (PubMed-24243147) (280 aa)
           
  0.954
MYB83
Myb domain protein 83 (343 aa)
           
  0.868
MYB58
Myb domain protein 58 (274 aa)
           
  0.868
MYB63
Myb domain protein 63 (294 aa)
           
  0.867
MYB85
Myb domain protein 85 (266 aa)
           
  0.863
IRX9
IRREGULAR XYLEM 9; Involved in the synthesis of the hemicellulose glucuronoxylan, a major component of secondary cell walls. Probably involved in the elongation of glucuronoxylan xylosyl backbone (351 aa)
           
  0.829
APL
ALTERED PHLOEM DEVELOPMENT; Transcription factor required for phloem identity. Has a dual role both in promoting phloem differentiation and in repressing xylem differentiation during vascular development. Regulates the expression of the transcription factor NAC045 (AC A4VCM0) (358 aa)
           
  0.762
IRX1
IRREGULAR XYLEM 1; Catalytic subunit of cellulose synthase terminal complexes (’rosettes’), required for beta-1,4-glucan microfibril crystallization, a major mechanism of the cell wall formation. Involved in the secondary cell wall formation. Required for the xylem cell wall thickening (985 aa)
     
   
  0.753
KNAT7
Homeobox protein knotted-1-like 7; May be involved in secondary cell wall biosynthesis (291 aa)
           
  0.739
GAUT12
Galacturonosyltransferase 12; Involved in pectin assembly and/or distribution, and in the synthesis of secondary wall glucuronoxylan. Probably involved in the synthesis of the glycosyl sequence at the glucuronoxylan reducing end. May be involved in synthesis of a complex glycan primer for xylan synthesis (535 aa)
           
  0.735
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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