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STRINGSTRING
NAC13 protein (Arabidopsis thaliana) - STRING interaction network
"NAC13" - NAC domain-containing protein 13 in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NAC13NAC domain-containing protein 13; Transcriptional activator activated by proteolytic cleavage through regulated intramembrane proteolysis (RIP). Involved in oxidative stress tolerance by mediating regulation of mitochondrial retrograde signaling during mitochondrial dysfunction. Interacts directly with the mitochondrial dysfunction DNA consensus motif 5’-CTTGNNNNNCA[AC]G-3’, a cis-regulatory elements of several mitochondrial retrograde regulation-induced genes, and triggers increased oxidative stress tolerance (528 aa)    
Predicted Functional Partners:
AOX1A
Encodes AOX1a, an isoform of alternative oxidase that is expressed in rosettes, flowers, and root. The alternative oxidase of plant mitochondria transfers electrons from the ubiquinone pool to oxygen without energy conservations. It is regulated through transcriptional control and by pyruvate. Plays a role in shoot acclimation to low temperature. Also is capable of ameliorating reactive oxygen species production when the cytochrome pathway is inhibited. AOX1a also functions as a marker for mitochondrial retrograde response (354 aa)
     
   
  0.850
TAG1
Membrane bound O-acyl transferase (MBOAT) family protein; Major contributor to triacylglycerol (TAG) synthesis and oil accumulation in seeds. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Can use palmitoyl-CoA and oleoyl-CoA as substrates. Can use oleoyl-CoA and linoleoyl-CoA as substrates. Has substrate preference for oleoyl-CoA compared to linoleoyl-CoA. Has complementary functions with PDAT1 that are essential for triacylglycerol synthesis and normal development of both seeds and pollen (520 aa)
     
        0.836
NAC088
NAC domain containing protein 88 (NAC088); Its function is described as sequence-specific DNA binding transcription factor activity; Involved in multicellular organismal development, regulation of transcription; Located in cellular_component unknown; Contains the following InterPro domains- No apical meristem (NAM) protein (InterPro-IPR003441); BEST Arabidopsis thaliana protein match is- NAC (No Apical Meristem) domain transcriptional regulator superfamily protein (TAIR-AT5G18037.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 3 [...] (147 aa)
           
  0.760
RCD1
Encodes a protein belonging to the (ADP-ribosyl)transferase domain-containing subfamily of WWE protein-protein interaction domain protein family. Superoxide radicals are necessary and sufficient to propagate cell death or lesion formation in rcd1 mutants. Without stress treatment, RCD1 is localized in the nucleus. Under high salt or oxidative stress, RCD1 is found not only in the nucleus but also in the cytoplasm (589 aa)
     
 
  0.759
NAC085
Uncharacterized protein F18O22_280; NAC domain containing protein 85 (NAC085); Its function is described as sequence-specific DNA binding transcription factor activity; Involved in multicellular organismal development, regulation of transcription; Contains the following InterPro domains- No apical meristem (NAM) protein (InterPro-IPR003441); BEST Arabidopsis thaliana protein match is- NAC domain containing protein 44 (TAIR-AT3G01600.1); Has 2068 Blast hits to 2065 proteins in 64 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 2068; Viruses - 0; Other Eukaryotes - 0 [...] (350 aa)
           
  0.646
NAC044
NAC domain containing protein 44 (NAC044); Its function is described as sequence-specific DNA binding transcription factor activity; Involved in multicellular organismal development, regulation of transcription; Contains the following InterPro domains- No apical meristem (NAM) protein (InterPro-IPR003441); BEST Arabidopsis thaliana protein match is- NAC domain containing protein 85 (TAIR-AT5G14490.1); Has 1967 Blast hits to 1962 proteins in 64 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1967; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (370 aa)
           
  0.646
UTR1
UDP-galactose/UDP-glucose transporter 1; Essential sugar transporter required for the transport of UDP-galactose and UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum, to ensure quality control of protein folding. Essential for pollen development and involved in embryo sac progress (332 aa)
           
  0.506
UTR3
UDP-galactose/UDP-glucose transporter 3; Essential sugar transporter required for the transport of UDP-glucose from the cytoplasm into the Golgi and the endoplasmic reticulum. Essential for pollen development and involved in embryo sac progress; Belongs to the nucleotide-sugar transporter family. UDP-galactose-UMP antiporter (TC 2.A.7.11) subfamily (331 aa)
           
  0.506
AT5G56960
Basic helix-loop-helix (bHLH) DNA-binding family protein; Its function is described as DNA binding, sequence-specific DNA binding transcription factor activity; Involved in response to chitin, regulation of transcription; Located in nucleus; Contains the following InterPro domains- Helix-loop-helix DNA-binding domain (InterPro-IPR001092), Helix-loop-helix DNA-binding (InterPro-IPR011598); BEST Arabidopsis thaliana protein match is- basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR-AT5G57150.4); Has 2180 Blast hits to 2174 proteins in 183 species- Archae - 0; Bacteria [...] (466 aa)
           
  0.491
FRU
Encodes a putative transcription factor that regulates iron uptake responses. mRNA is detected in the outer cell layers of the root and accumulates in response to iron deficiency. The expression of many iron-regulated genes is dependent on FIT1. It specifically regulates FRO2 at the level of mRNA accumulation and IRT1 at the level of protein accumulation.Similar to FER in tomato and is a regulator of iron uptake (318 aa)
           
  0.491
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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