STRINGSTRING
GTL1 protein (Arabidopsis thaliana) - STRING interaction network
"GTL1" - GT-2-like 1 in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTL1GT-2-like 1; Transcription repressor that binds specific DNA sequence such as GT3 box 5’-GGTAAA-3’ in the SDD1 promoter. Negative regulator of water use efficiency (WUE) via the promotion of stomatal density and distribution by the transcription repression of SDD1. Regulates the expression of several cell cycle genes and endoreduplication, especially in trichomes where it prevents ploidy-dependent plant cell growth (669 aa)    
Predicted Functional Partners:
SDD1
Subtilase-like protein; Serine protease involved in the negative regulation of stomatal density and distribution. Not active on EPFL6 (AC Q1PEY6) (PubMed-20056678). Positive regulator of water use efficiency (WUE) (775 aa)
           
  0.807
AT2G38250
DNA-binding protein; Probable transcription factor that may play a role in the induction of CAM4 in response to pathogen and salt (289 aa)
           
  0.637
AT3G10030
Aspartate/glutamate/uridylate kinase-like protein (542 aa)
           
  0.635
ASIL1
6B-interacting protein 1-like 1; Transcription repressor that binds specific DNA sequence such as the GT-box-like motif 5’-CGTGATT-3’ in the AT2S3 promoter. Negative regulator of seed maturation genes during seed germination and seedling development. May target GT-box-containing embryonic genes by competing with the binding of transcriptional activators to this promoter region (PubMed-19155348). Contributes to the maintenance and control of seed filling (PubMed-22231199) and may repress the maturation program during early embryogenesis (PubMed-21330492) (383 aa)
           
  0.603
XXT3
Xyloglucan 6-xylosyltransferase; Probable xyloglucan xylosyltransferase involved in the biosynthesis of xyloglucan (457 aa)
           
  0.601
CRLK1
Protein kinase family protein; Required for cold tolerance, via the activation of MAP kinases activity (PubMed-20026608, PubMed-20724845). Phosphorylates and activates MEKK1 in response to cold in a calcium-dependent manner (PubMed-23857079) (440 aa)
           
  0.491
PFD3
Prefoldin 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity) (195 aa)
           
  0.491
AT2G33550
Gt-2-related protein; Transcriptional repressor that binds DNA and plays a negative role in regulating microbe-associated molecular patterns- (MAMPs, e.g. flg22, elf18, chitin, and LPS) triggered immunity (PTI) by negatively regulating immune gene expression (314 aa)
           
  0.479
ASIL2
Arabidopsis 6B-interacting protein 1-like 2; Transcription regulator that may repress the maturation program during early embryogenesis (443 aa)
           
  0.472
AT2G26720
Cupredoxin superfamily protein (206 aa)
           
  0.470
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (16%) [HD]