• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
AT1G33420 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G33420" - RING/FYVE/PHD zinc finger superfamily protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G33420RING/FYVE/PHD zinc finger superfamily protein; Its function is described as DNA binding, zinc ion binding; Involved in regulation of transcription, DNA-dependent; Expressed in 22 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains- Zinc finger, PHD-type, conserved site (InterPro-IPR019786), Zinc finger, PHD-type (InterPro-IPR001965), Zinc finger, FYVE/PHD-type (InterPro-IPR011011), Zinc finger, PHD-finger (InterPro-IPR019787); BEST Arabidopsis thaliana protein match is- RING/FYVE/PHD zinc finger superfamily protein (TAIR-AT1G66170.1); Has 734 Bl [...] (697 aa)    
Predicted Functional Partners:
AT3G52250
Duplicated homeodomain-like superfamily protein; Encodes a protein with a putative role in mRNA splicing (1656 aa)
     
 
  0.867
AT2G38580
Mitochondrial ATP synthase D chain-related protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in 23 plant structures; Expressed during 13 growth stages; Has 74576 Blast hits to 44417 proteins in 2485 species- Archae - 658; Bacteria - 11770; Metazoa - 34102; Fungi - 5844; Plants - 3204; Viruses - 216; Other Eukaryotes - 18782 (source- NCBI BLink) (482 aa)
           
  0.750
HOS15
WD40 repeat-containing protein HOS15; Encodes a WD-40 protein involved in histone deacetylation in response to abiotic stress.Identified in a screen for mutations with altered expression of stress induced genes. Functions as a repressor of cold tolerance induced genes. Loss of function mutants are hypersensitive to freezing (613 aa)
     
 
  0.743
AT5G08450
Uncharacterized protein At5g08450; Contains the following InterPro domains- Histone deacetylation protein Rxt3 (InterPro-IPR013951); Has 30201 Blast hits to 17322 proteins in 780 species- Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source- NCBI BLink) (918 aa)
       
 
  0.705
UPL4
E3 ubiquitin-protein ligase UPL4; Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins (1502 aa)
     
        0.702
KAK
HEAT repeat ;HECT-domain (ubiquitin-transferase); Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the repression of endoreduplication process and the cell morphogenesis in the trichomes (1888 aa)
     
        0.702
PIE1
Encodes a protein similar to ATP-dependent, chromatin-remodeling proteins of the ISWI and SWI2/SNF2 family. Genetic analyses suggest that this gene is involved in multiple flowering pathways. Mutations in PIE1 results in suppression of FLC-mediated delay of flowering and causes early flowering in noninductive photoperiods independently of FLC. PIE1 is required for expression of FLC in the shoot apex but not in the root.Along with ARP6 forms a complex to deposit modified histone H2A.Z at several loci within the genome. This modification alters the expression of the target genes (i.e. FL [...] (2055 aa)
     
 
  0.635
HDA6
Histone deacetylase 6; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Might remove acetyl residues only from specific targets, such as rDNA repeats or complex transgenes. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Required for rRNA gene silencing in nucleolar dominance. Plays a role in transgene silencing, but this e [...] (471 aa)
       
 
  0.610
HDA7
Histone deacetylase 7; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. May be involved in flowering induction. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily (409 aa)
       
 
  0.610
HD1
Encodes a histone deacetylase that enhances AtERF7-mediated transcriptional repression. Binds SIM3 and ERF7. Expressed in the nucleus in most tissues examined and throughout the life of the plant. Involved in jasmonic acid and ethylene dependent pathogen resistance. The sequence in GenBank has 17 AG dinucleotide repeats missing, which is also missing in Ler shotgun sequence from Cereon. Although it is annotated to be in Columbia, the GB sequence is probably not of Columbia origin. Plays a role in embryogenesis as mutants grown at higher temperatures display abnormalities in the organi [...] (501 aa)
       
 
  0.610
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (9%) [HD]