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At1g34140 protein (Arabidopsis thaliana) - STRING interaction network
"At1g34140" - poly(A) binding protein 1 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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textmining
co-expression
protein homology
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At1g34140poly(A) binding protein 1; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation (By similarity) (407 aa)    
Predicted Functional Partners:
AT2G39260
RNA binding protein; Recruited by UPF3 associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Required for plant development and adaptatio [...] (1181 aa)
         
  0.979
UPF3
Smg-4/UPF3-like protein; Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. Binds spliced mRNA upstream of exon-exon junctions (By similarity). Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nons [...] (484 aa)
       
  0.972
SMG7
Telomerase activating protein Est1; Plays multiple roles in growth and development. Involved in nonsense-mediated mRNA decay (NMD). May provide a link to the mRNA degradation machinery to initiate NMD and serve as an adapter for UPF proteins function. Required for meiotic progression through anaphase II of pollen mother cells. May counteract cyclin- dependent kinase (CDK) activity at the end of meiosis. May play a role in plant defense through its involvement in NMD (1059 aa)
       
  0.962
EIF4A-III
Eukaryotic initiation factor 4A-III; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity) (408 aa)
   
  0.959
LBA1
LOW-LEVEL BETA-AMYLASE 1; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (premature termination codon PTC) by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Eliminates the production of nonsense-containing RNAs (ncRNAs). Required for plant development and adaptation to environmental stresses, including plant defense and response to wounding (1254 aa)
       
  0.959
ABH1
ABA HYPERSENSITIVE 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing and RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs). The CBC complex is involved in miRNA-mediated RNA interference and is required for primary miRNA processing. In the CBC complex, ABH1/CBP80 does not bind directly capped RNAs (m7GpppG-capped RNA) but is required to stabilize the movement of the N-terminal loop of CBP20 and lock the CBC into a high affinity cap-binding state with the cap str [...] (848 aa)
       
  0.951
AT3G26560
ATP-dependent RNA helicase, putative; May be involved in pre-mRNA splicing (1168 aa)
     
 
  0.944
AT1G51380
DEAD-box ATP-dependent RNA helicase 34; ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity) (392 aa)
   
  0.943
AT1G18070
G1 to S phase transition protein (543 aa)
     
  0.939
EIF3E
Eukaryotic translation initiation factor 3E; Essential protein (PubMed-18067529, PubMed-20444226). Component of the eukaryotic translation initiation factor 3 (eIF- 3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome (Potential). Regulates negatively translation during flower development (PubMed-18067529) (441 aa)
     
    0.935
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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