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EPF2 protein (Arabidopsis thaliana) - STRING interaction network
"EPF2" - EPIDERMAL PATTERNING FACTOR 2 in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
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protein homology
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EPF2EPIDERMAL PATTERNING FACTOR 2; Controls stomatal patterning. Regulates the number of cells that enter, and remain in, the stomatal lineage by inhibiting protodermal cells from adopting the meristemoid mother cell (MMC) fate in a non-cell-autonomous manner. Mediates stomatal development inhibition. MEPF2- mobile signal controlling stomatal development in a non-cell-autonomous manner (PubMed-22241782). Uses ERECTA as major receptor (PubMed-22241782). Inactivated by cleavage by CRSP (AC Q9LNU1) (PubMed-25043023). May act by competing with somatogen (AC Q9SV72) for the same receptor, TMM ( [...] (120 aa)    
Predicted Functional Partners:
TMM
TOO MANY MOUTHS; Promotes cell fate progression in stomatal development. In leaves, needed to correctly orient spacing divisions, to limit the number of asymmetric divisions in neighbor cells, and to promote the asymmetric (amplifying) divisions of meristemoids. In stems, promotes the conversion of meristemoids into guard mother cells (GMC). Modulates probably the activity of the ligand- receptor pairs EPF2-ERECTA and EPF1-ERL1 via heterodimerization (PubMed-22241782) (496 aa)
     
 
  0.985
STOMAGEN
STOMAGEN; Stomagen- Positively regulates stomatal density and patterning. May act by competing with either EPF1 (AC Q8S8I4) or EPF2 (AC Q8LC53) for the same receptor, TMM (AC Q9SSD1). Not cleaved by the protease CRSP (AC Q9LNU1) (PubMed-25043023) (102 aa)
           
  0.959
ERL1
ERECTA-like 1; Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ER and ERL2. Redundantly involved with ER in procambial development regulation. Forms a functional ligand-receptor pair with EPF1 (AC Q8S8I4) (PubMed-22241782) (966 aa)
     
 
  0.954
MUTE
MUTE; Transcription factor. Together with FMA and SPCH, regulates the stomata formation. Required for the differentiation of stomatal guard cells, by promoting successive asymmetric cell divisions and the formation of guard mother cells. Promotes the conversion of the leaf epidermis into stomata (202 aa)
     
   
  0.872
SPCH
SPEECHLESS; Transcription factor. Together with FMA and MUTE, regulates the stomata formation. Required for the initiation and the formation of stomata, by promoting the first asymmetric cell divisions (364 aa)
     
   
  0.864
TE1
ERECTA; Receptor kinase that, together with ERL1 and ERL2, regulates aerial architecture, including inflorescence (e.g. shoot apical meristem-originating organ shape, elongation of the internode and pedicels, and adaxial-abaxial polarity), and stomatal patterning (e.g. density and clustering), probably by tuning cell division and expansion. Redundantly involved with ERL1 in procambial development regulation. Forms a functional ligand- receptor pair with EPF2 (AC Q8LC53) (PubMed-22241782). Modulates plant transpiration efficiency by controlling stomatal density, leaf photosynthetic capa [...] (976 aa)
       
 
  0.860
ERL2
ERECTA-like 2; Receptor kinase that regulates inflorescence architecture and organ shape as well as stomatal patterning, including density and clustering, together with ERL1 and ER (967 aa)
     
   
  0.839
BASL
BREAKING OF ASYMMETRY IN THE STOMATAL LINEAGE; Regulates asymmetric cell division, especially in stomatal-lineage cells, probably by modulating subcellular polarization of POLAR (262 aa)
     
   
  0.829
SCRM2
SCREAM 2; Mediates stomatal differentiation in the epidermis probably by controlling successive roles of SPCH, MUTE, and FAMA (450 aa)
     
   
  0.814
CLL2
CHALLAH-LIKE 2; Acts primarily as positive regulator of inflorescence growth. Endodermal expression is sufficient for proper inflorescence architecture (PubMed-22474391). Redundantly involved with EPFL6 in procambial development regulation. Controls stomatal patterning. Mediates stomatal development inhibition. TMM (AC Q9SSD1) functions to dampen or block CLL2 signaling. Acts as growth-regulatory ligand for ERECTA family receptors (109 aa)
           
  0.809
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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