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CYCB1;5 protein (Arabidopsis thaliana) - STRING interaction network
"CYCB1;5" - Cyclin B in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CYCB1;5Cyclin B (491 aa)    
Predicted Functional Partners:
WEE1
WEE1 kinase homolog; Cell cycle regulatory kinase that is not rate-limiting for cycle progression under normal growth conditions. Transcriptionally activated upon DNA stress or damage in an ATR- or ATM-dependent manner. Once activated, inhibits plant growth by arresting dividing cells in the G2 phase before proceeding into mitosis. Down-regulates CDKA-1 and CDKD-2 by tyrosine phosphorylation. May target principally CDKA-1 (500 aa)
     
  0.930
ATR
Serine/threonine-protein kinase ATR; Probable serine/threonine kinase. Plays a central role in cell-cycle regulation by transmitting DNA damage signals to downstream effectors of cell-cycle progression. May recognize the substrate consensus sequence [ST]-Q and phosphorylate histone variant H2AX to form H2AXS139ph at sites of DNA damage, thereby regulating DNA damage response mechanism. Seems to be required for the G2-phase checkpoint in response to replication blocks but not absolutely required in the G2-arrest response to double-strand breaks. May also be involved in the meiosis proce [...] (2702 aa)
       
  0.914
CDKB1;1
Cyclin-dependent kinase B1-1; May control G2/M (mitosis) phase progression. Plays a role in regulating seedling growth in darkness via regulation of hypocotyl cell elongation and cotyledon cell development. Plays a role in stomatal development. Required to suppress endoreduplication (309 aa)
     
  0.892
CDC2
Cell division control 2; Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis (294 aa)
     
  0.891
CDKB1;2
Cyclin-dependent kinase B1-2 (311 aa)
     
  0.887
CKS1
Cyclin-dependent kinase-subunit 1; Associates with cyclin-dependent kinases (CDKs) and plays an essential role in the regulation of the cell cycle that affects plant growth rate. May inhibit both the G1/S and G2/M phases (87 aa)
     
 
  0.882
CDC20.2
Cell division cycle 20.2; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle (447 aa)
     
 
  0.875
CDKB2;1
Cyclin-dependent kinase B2-1 (313 aa)
     
  0.871
CDKB2;2
Cyclin-dependent kinase B2-2 (315 aa)
     
  0.865
APC10
Anaphase promoting complex 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating the ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several other aspects of development. Involved in the control of endoreduplication (192 aa)
     
 
  0.857
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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