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TT1 protein (Arabidopsis thaliana) - STRING interaction network
"TT1" - Transparent testa 1 in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
TT1Transparent testa 1; May act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat (PubMed-21477081). Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development (PubMed-21477081) (303 aa)    
Predicted Functional Partners:
TT2
TRANSPARENT TESTA 2; Transcription activator, when associated with BHLH2/EGL3/MYC146, BHLH12/MYC1, or BHLH42/TT8. Involved in the control of flavonoid late metabolism in developing siliques. Plays a key role in determining the tissue-specific activation of leucoanthocyanidin reductase (BANYULS) (258 aa)
     
  0.980
AT2G20050
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein (1094 aa)
     
  0.971
TT12
TRANSPARENT TESTA 12; Acts as a flavonoid/H(+)-antiporter that control the vacuolar sequestration of flavonoids in the seed coat endothelium (PubMed-11283341, PubMed-17601828). Could transport the anthocyanin cyanidin-3-O-glucoside (PubMed-17601828) and epicatechin 3’-O-glucoside (PubMed-19684242) in vitro (507 aa)
     
   
  0.920
TT8
TRANSPARENT TESTA 8; Transcription activator, when associated with MYB75/PAP1 or MYB90/PAP2. Involved in the control of flavonoid pigmentation. Plays a key role in regulating leucoanthocyanidin reductase (BANYULS) and dihydroflavonol-4-reductase (DFR). Not required for leucoanthocyanidin dioxygenase (LDOX) expression (518 aa)
     
   
  0.919
TT16
TRANSPARENT TESTA16; Transcription factor involved in the developmental regulation of the endothelium and in the accumulation of proanthocyanidins (PAs) or condensed tannins which give the seed its brown pigmentation after oxidation. Necessary for the normal activation of the BANYULS promoter in the endothelium body (252 aa)
     
  0.905
DFR
Dihydroflavonol 4-reductase (382 aa)
     
   
  0.852
BAN
BANYULS; Involved in the biosynthesis of condensed tannins. Converts cyanidin into (-)-epicatechin as the major product (340 aa)
     
   
  0.848
TTG2
TRANSPARENT TESTA GLABRA 2; Transcription factor. Interacts specifically with the W box (5’-(T)TGAC[CT]-3’), a frequently occurring elicitor- responsive cis-acting element. Regulates trichome development, production of mucilage and tannin in seed coats, and maybe root hair development (429 aa)
     
   
  0.847
TT10
Laccase-15; Lignin degradation and detoxification of lignin-derived products (By similarity). Involved in lignin synthesis in seed coats, in seed coat permeability, in seed germination, and in root elongation. Required for the seed coat (testa) brown pigmentation by mediating the polymerization of proanthocyanidin (tannin) from its monomer precursor epicatechin. Promotes sligthly seed dormancy (565 aa)
       
 
  0.845
TTG1
TRANSPARENT TESTA GLABRA 1; May regulate MYC transcription factors. Involved in epidermal cell fate specification such as trichome and root hair development, seed mucilage production, and anthocyanin biosynthesis by acting at the dihydroflavonol-4-reductase (DFR) step. Together with GL1 and GL3, promotes trichome formation. Activates the transcription of GL2 (341 aa)
           
  0.829
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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