STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G36050Endoplasmic reticulum vesicle transporter protein; Its function is described as molecular_function unknown; Involved in fatty acid biosynthetic process; Located in plasma membrane; Expressed in 25 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: Protein of unknown function DUF1692 (InterPro:IPR012936); BEST Arabidopsis thaliana protein match is: Endoplasmic reticulum vesicle transporter protein (TAIR:AT1G22200.1); Has 1210 Blast hits to 1080 proteins in 199 species: Archae - 0; Bacteria - 0; Metazoa - 398; Fungi - 262; Plants - 277; Viruses [...] (489 aa)    
Predicted Functional Partners:
AT5G50110
S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; Its function is described as rRNA methyltransferase activity; Involved in rRNA processing; Located in cytoplasm; Expressed in 24 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains: rRNA small subunit methyltransferase G (InterPro:IPR003682); Has 6840 Blast hits to 6840 proteins in 2435 species: Archae - 0; Bacteria - 5096; Metazoa - 2; Fungi - 0; Plants - 38; Viruses - 0; Other Eukaryotes - 1704 (source: NCBI BLink)
  
  
 0.925
AT1G78010
tRNA modification GTPase, putative; Its function is described as GTP binding, GTPase activity; Involved in small GTPase mediated signal transduction, tRNA modification; Located in intracellular; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Small GTP-binding protein (InterPro:IPR005225), Ras GTPase (InterPro:IPR001806), tRNA modification GTPase TrmE (InterPro:IPR004520), GTP-binding protein TrmE, N-terminal (InterPro:IPR018948), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match [...]
  
 
 0.814
emb2738
GTP-binding family protein; Embryo defective 2738 (emb2738); Its function is described as GTP binding; Involved in embryo development ending in seed dormancy; Located in chloroplast; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: GTP-binding, EngA (InterPro:IPR016484), Small GTP-binding protein (InterPro:IPR005225), GTP1/OBG (InterPro:IPR006073), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: GTP binding;GTP binding (TAIR:AT5G39960.1); Has 46668 Blast hits to 25884 protei [...]
  
 
 0.814
AT5G39960
GTP binding;GTP binding; Its function is described as GTP binding; Located in intracellular; Expressed in 21 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: GTP-binding, EngA (InterPro:IPR016484), Small GTP-binding protein (InterPro:IPR005225), GTP1/OBG (InterPro:IPR006073), Guanylate kinase (InterPro:IPR008144), GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: GTP-binding family protein (TAIR:AT3G12080.1); Has 25797 Blast hits to 22413 proteins in 2944 species: Archae - 203; Bacteria - 192 [...]
  
 
 0.814
PDIL1-5
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Unlike several other PDI family members, transcript levels for this gene are not up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin)
   
 
 0.638
PDIL5-1
Protein disulfide-isomerase 5-1; Acts as a protein-folding catalyst that interacts with nascent polypeptides to catalyze the formation, isomerization, and reduction or oxidation of disulfide bonds
   
 
 0.624
AT1G51310
transferases;tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferases; Its function is described as tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, transferase activity; Involved in tRNA processing, RNA processing; Located in chloroplast, cytoplasm; Expressed in 23 plant structures; Expressed during 13 growth stages; Contains the following InterPro domains: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), tRNA-specific 2-thiouridylase (InterPro:IPR004506); Has 8544 Blast hits to 8538 proteins in 2600 species: Archae - 0; Bacteria - 5626; Me [...]
  
 
 0.558
PDXH
Pyridoxine/pyridoxamine 5'-phosphate oxidase 1, chloroplastic; Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). Involved in the PLP salvage pathway. Has a higher preference for PNP over PMP. May also catalyze the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; In the N-terminal section; belongs to th [...]
  
  
 0.543
PDIL1-2
Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response
   
 
 0.540
P5CS1
Encodes a delta1-pyrroline-5-carboxylate synthase that catalyzes the rate-limiting enzyme in the biosynthesis of proline. Gene is expressed in reproductive organs and tissues under non-stress conditions but in the whole plant under water-limiting condition. Expression is also induced by abscisic acid and salt stress in a light-dependent manner. P5CS1 appears to be involved in salt stress responses related to proline accumulation, including protection from reactive oxidative species. P5CS1 appears to be present in different cells and/or different subcellular locations from P5CS2 in a ti [...]
      
 0.538
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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