• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
AT1G36280 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G36280" - L-Aspartase-like family protein in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G36280L-Aspartase-like family protein; Its function is described as N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity, catalytic activity; Involved in purine ribonucleotide biosynthetic process, purine base biosynthetic process, IMP biosynthetic process; Located in chloroplast; Contains the following InterPro domains- Adenylosuccinate lyase C-terminal/plant (InterPro-IPR013539), L-Aspartase-like (InterPro-IPR008948), Adenylosuccinate lyase (InterPro-IPR004769), Fumarate lyase, conserved site (InterPro-IPR020557), Lyase 1, N-terminal (InterPro-IPR022761), Fumarate lyase (InterP [...] (527 aa)    
Predicted Functional Partners:
ADSS
Adenylosuccinate synthetase, chloroplastic; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (490 aa)
   
 
  0.999
AT2G35040
AICARFT/IMPCHase bienzyme family protein; Its function is described as phosphoribosylaminoimidazolecarboxamide formyltransferase activity, IMP cyclohydrolase activity, catalytic activity; Involved in response to cold, purine nucleotide biosynthetic process; Located in stromule, chloroplast, chloroplast stroma; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- AICARFT/IMPCHase bienzyme, transformylase domain (InterPro-IPR013982), AICARFT/IMPCHase bienzyme (InterPro-IPR002695), MGS-like (InterPro-IPR011607); Has 10802 Blast hits [...] (596 aa)
   
  0.997
FAC1
AMP deaminase, putative / myoadenylate deaminase, putative; Encodes a protein with in vitro AMP deaminase activity that is involved in embryogenesis. Homozygous mutant embryos fail to develop past the zygote stage (839 aa)
   
 
  0.994
PUR5
Phosphoribosylformylglycinamidine cyclo-ligase, chloroplastic; Encoding phosphoribosylformylglycinamidine cyclo-ligase (syn. AIR synthetase)that phosphorylates 5-phosphoribosyl-N-formylglycinamidine (FGAM) to form 5-aminoimidazole ribonucleotide (AIR) (389 aa)
   
 
  0.990
PUR2
Phosphoribosylamine--glycine ligase, chloroplastic; Glycinamide ribonucleotide synthetase (GAR synthetase) that catalyzes the conversion of phosphoribosyl amine to phosphoribosyl glycineamide (532 aa)
   
 
  0.990
PUR7
Phosphoribosylaminoimidazole-succinocarboxamide synthase, chloroplastic; 5’-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole synthetase (PUR7, syn. SAICAR synthetase), catalyzes aspartate addition at the alpha-amino group to the growing purine backbone (411 aa)
   
  0.989
ASE2
Encodes glutamine 5-phosphoribosylpyrophosphate amidotransferase. Mutants are deficient in leaf, but not cotyledon, plastid and palisade cell development. Mutants exhibit defective chloroplast development under non-low light, suggesting that the defect in chloroplast development is caused by photo-oxidative damage; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (561 aa)
   
 
  0.984
ADK2
Encodes adenosine kinase 2 (ADK2), a typical, constitutively expressed housekeeping enzyme. Shows a high sequence identity with ADK1. Involved in salvage synthesis of adenylates and methyl recycling. Enzyme activity is substantially inhibited in roots, siliques and dry seeds by an unknown compound. May contribute to cytokinin interconversion; Belongs to the carbohydrate kinase PfkB family (345 aa)
   
  0.976
At3g09820
Adenosine kinase 1; ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Essential to sustain methyl recycling (344 aa)
   
  0.975
APT5
Adenine phosphoribosyltransferase 5; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. May contribute to the recycling of adenine into adenylate nucleotides and the inactivation of cytokinins by phosphoribosylation. Possesses low activity toward adenine, but can efficiently convert cytokinins from free bases (active form) to the corresponding nucleotides (inactive form); Belongs to the purine/pyrimidine phosphoribosyltransferase family (191 aa)
   
  0.974
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (13%) [HD]