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HCS2 protein (Arabidopsis thaliana) - STRING interaction network
"HCS2" - Holocarboxylase synthetase 2 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HCS2Holocarboxylase synthetase 2; Seems to have no or limited implication in biotin- dependent carboxylase biotinylation in planta (329 aa)    
Predicted Functional Partners:
ACC2
Acetyl-CoA carboxylase 2; Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways including fatty acid elongation (2355 aa)
   
  0.995
ACC1
Acetyl-CoA carboxylase 1; Multifunctional enzyme that catalyzes the carboxylation of acetyl-CoA, forming malonyl-CoA, which is used in the plastid for fatty acid synthesis and in the cytosol in various biosynthetic pathways including fatty acid elongation. Required for very long chain fatty acids elongation. Necessary for embryo and plant development. Plays a central function in embryo morphogenesis, especially in apical meristem development. Involved in cell proliferation and tissue patterning. May act as a repressor of cytokinin response (2254 aa)
   
  0.995
BIO2
Radical SAM superfamily protein; Catalyzes the conversion of dethiobiotin to biotin (378 aa)
       
  0.974
AT5G64780
Uncharacterised conserved protein UCP009193; Contains the following InterPro domains- Uncharacterised conserved protein UCP009193 (InterPro-IPR016549); BEST Arabidopsis thaliana protein match is- Uncharacterised conserved protein UCP009193 (TAIR-AT4G09830.1); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source- NCBI BLink) (175 aa)
           
  0.967
MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial; Biotin-attachment subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism (734 aa)
       
  0.963
MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism (587 aa)
       
  0.952
BCCP2
Biotin carboxyl carrier protein of acetyl-CoA carboxylase 2, chloroplastic; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (255 aa)
     
 
  0.936
CAC1
Biotin carboxyl carrier protein of acetyl-CoA carboxylase 1, chloroplastic; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA (280 aa)
     
 
  0.930
HCS1
Biotin--protein ligase 1, chloroplastic; Plays a major role in biotin-dependent carboxylase biotinylation. Catalyzes the addition of biotin to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase and can also biotinylate methylcrotonyl-CoA carboxylase. Is responsible for most, if not all, biotin--protein ligase activity in Arabidopsis. Is essential for plant viability and required for ovule development (367 aa)
   
   
0.902
AT2G37400
Tetratricopeptide repeat (TPR)-like superfamily protein; Its function is described as binding; Involved in biological_process unknown; Located in chloroplast thylakoid lumen, chloroplast envelope; Expressed in 21 plant structures; Expressed during 12 growth stages; Contains the following InterPro domains- Tetratricopeptide-like helical (InterPro-IPR011990), Tetratricopeptide repeat-containing (InterPro-IPR013026), Tetratricopeptide repeat (InterPro-IPR019734); BEST Arabidopsis thaliana protein match is- Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR-AT3G53560.1); Has 215 [...] (333 aa)
           
  0.770
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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