STRINGSTRING
AT1G40129 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G40129" - Uncharacterized protein in Arabidopsis thaliana
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AT1G40129Uncharacterized protein (567 aa)    
Predicted Functional Partners:
TOP1BETA
DNA topoisomerase 1 beta (917 aa)
           
  0.955
AT2G19920
RNA-dependent RNA polymerase family protein; Probably involved in the RNA silencing pathway and required for the generation of small interfering RNAs (siRNAs) (927 aa)
           
  0.676
TOP1ALPHA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5’-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Final [...] (933 aa)
           
  0.635
YKT61
VAMP-like protein YKT61 (221 aa)
       
 
  0.602
DMS3
DEFECTIVE IN MERISTEM SILENCING 3; Component of the RNA-directed DNA methylation (RdDM) machinery, probably by facilitating an RNAi-mediated epigenetic modification involving secondary siRNAs and spreading of DNA methylation, thus leading to gene silencing. Involved in the assembly of RNA polymerase V (Pol V) transcription initiation or elongation complexes at the chromatin, as a component of the DDR complex. Required for de novo DNA methylation (420 aa)
           
  0.554
AT3G42860
CCHC-type zinc knuckle protein; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (372 aa)
       
 
  0.518
SDE3
SILENCING DEFECTIVE; Probable RNA helicase required for post-transcriptional gene silencing (PTGS), a process that provides protection in plants against virus infection and can suppress expression of transgenes. Plays a central role in RNA interference (RNAi) process, a process that mediates mRNA destruction of translational repression. Required for the assembly of the RISC complex, a complex required for target RNA destruction or repression. May be required in the RISC assembly to unwind miRNAs, in the production of single-stranded miRNA from the double-stranded miRNA, a key step in R [...] (1002 aa)
           
  0.456
SUVH6
SU(VAR)3-9 homolog 6; Histone methyltransferase. Methylates ’Lys-9’ of histone H3. H3 ’Lys-9’ methylation represents a specific tag for epigenetic transcriptional repression. Seems to act preferentially on dsMRNA (790 aa)
           
  0.453
EIF4A1
Translational initiation factor 4A-1 (415 aa)
           
  0.449
SUVH5
SU(VAR)3-9 homolog 5; Histone methyltransferase. Methylates ’Lys-9’ of histone H3. H3 ’Lys-9’ methylation represents a specific tag for epigenetic transcriptional repression (794 aa)
           
  0.448
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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