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AT1G42470 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G42470" - Patched family protein in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
AT1G42470Patched family protein (1272 aa)    
Predicted Functional Partners:
NPC1
Phospholipase C (533 aa)
     
   
  0.960
CYP710A1
Cytochrome P450, family 710, subfamily A; Required to form the C-22 double bond in the sterol side chain. Possesses in vitro C-22 desaturase activity toward beta- sitosterol and produces stigmasterol. No activity with campesterol (495 aa)
           
  0.632
BGLU26
PENETRATION 2; Possesses beta-glucosidase activity toward 4-methyl- umbelliferyl-beta-D-glucoside in vitro. Possesses myrosinase activity toward indol-3-yl-methylglucosinolate (I3M) and 4- methoxy-indol-3-yl-methylglucosinolate (4MO-I3M) in vivo (PubMed-19095900). Component of an inducible preinvasion resistance mechanism that prevents penetration of the nonhost fungal species B.graminis and E.pisi (PubMed-16293760). Involved in indole glucosinolate (IGS) activation during pattern-triggered immunity (PTI). Functions as myrosinase for the breakdown of flg22-triggered IGS. Required for b [...] (560 aa)
           
  0.603
S1P
SITE-1 protease; Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL motif. Targets the membrane-associated BZIP17 factor, which functions as a stress sensor and transducer in a signaling pathway that resembles an ER stress response. Following salt stress, BZIP17 is cleaved by SBT6.1 (S1P) and S2P at the C-terminus and the N-terminal bZIP com [...] (1038 aa)
     
 
  0.502
NHO1
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Required for resistance to nonhost Pseudomonas bacteria and to the pathogenic fungus B.cinerea (522 aa)
     
      0.494
SNAP33
SNAP25 homologous protein SNAP33; t-SNARE involved in diverse vesicle trafficking and membrane fusion processes, including cell plate formation. May function in the secretory pathway (300 aa)
           
  0.475
HAT24
Synaptobrevin-related protein 1; Involved in the targeting and/or fusion of transport vesicles to their target membrane (229 aa)
           
  0.475
ABCG36
PENETRATION 3; Key factor that controls the extent of cell death in the defense response. Neccessary for both callose deposition and glucosinolate activation in response to pathogens. Required for limiting invasion by nonadapted powdery mildews. Confers resistance to cadmium (Cd) and lead (Pb), probably as an efflux pump of Cd2+ or Cd conjugates, and possibly, of chemicals that mediate pathogen resistance (1469 aa)
     
 
  0.442
VSR1
Vacuolar-sorting receptor 1; Vacuolar-sorting receptor (VSR) involved in clathrin- coated vesicles sorting from Golgi apparatus to vacuoles. Required for the sorting of 12S globulin, 2S albumin and maybe other seed storage proteins to protein storage vacuoles (PSVs) in seeds. May also be implicated in targeting N-terminal propeptide containing proteins to lytic vacuoles (623 aa)
           
  0.407
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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