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hemb2 protein (Arabidopsis thaliana) - STRING interaction network
"hemb2" - Porphobilinogen synthase in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hemb2Porphobilinogen synthase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity) (406 aa)    
Predicted Functional Partners:
GSA2
Glutamate-1-semialdehyde 2,1-aminomutase 2; Transaminase converting glutamate 1-semialdehyde (GSA) to 5-aminolevulinate (ALA). Involved in the biosynthesis of tetrapyrroles (By similarity) (472 aa)
 
 
  0.997
GSA1
Glutamate-1-semialdehyde-2,1-aminomutase; Transaminase converting glutamate 1-semialdehyde (GSA) to 5-aminolevulinate (ALA). Involved in the biosynthesis of tetrapyrroles (474 aa)
 
 
  0.997
HEMC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (382 aa)
 
  0.995
HEMA2
glutamyl-tRNA reductase 2; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA). Probably involved in wound-induced supply of heme to defensive hemoproteins outside plastids (530 aa)
 
 
  0.966
HEMA1
glutamyl-tRNA reductase 1; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA). Probably involved in the tetrapyrrole synthesis required for the chlorophyll biosynthesis (543 aa)
 
 
  0.945
UPM1
Urophorphyrin methylase 1 (369 aa)
 
 
  0.931
hemf2
Coproporphyrinogen III oxidase; Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) (240 aa)
   
   
  0.912
HEMA3
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (524 aa)
 
 
  0.902
HEMB1
Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity) (430 aa)
   
   
 
0.901
HEME1
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (418 aa)
 
 
  0.851
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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