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CYCA3;2 protein (Arabidopsis thaliana) - STRING interaction network
"CYCA3;2" - cyclin-A3-2 in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CYCA3;2cyclin-A3-2 (372 aa)    
Predicted Functional Partners:
WEE1
WEE1 kinase homolog; Cell cycle regulatory kinase that is not rate-limiting for cycle progression under normal growth conditions. Transcriptionally activated upon DNA stress or damage in an ATR- or ATM-dependent manner. Once activated, inhibits plant growth by arresting dividing cells in the G2 phase before proceeding into mitosis. Down-regulates CDKA-1 and CDKD-2 by tyrosine phosphorylation. May target principally CDKA-1 (500 aa)
     
  0.997
CDC2
Cell division control 2; Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis (294 aa)
     
  0.996
PRL
PROLIFERA; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (By similarity). Required for megagametophyte and embryo development (716 aa)
     
  0.991
CDC6
Cell division control 6; May be involved in the initiation of DNA replication. May play a role in endoreduplication. Could act as one of the factors that contributes to maintain endoreduplication competence (539 aa)
     
  0.990
APC4
Anaphase promoting complex 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex controls several key steps in the cell cycle by mediating ubiquitination and subsequent degradation of target proteins such as cyclins. The APC/C complex is required for the female gametophyte development and is involved in several aspect of development by controlling cell division and cell elongation. Involved in the control of endoreduplica [...] (777 aa)
     
  0.989
MCM5
MINICHROMOSOME MAINTENANCE 5; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells (727 aa)
     
  0.985
RBR1
Retinoblastoma-related 1; Key regulator of entry into cell division. Acts as a transcription repressor of E2F target genes, whose activity is required for progress from the G1 to the S phase of the cell cycle. Hyperphosphorylation by CDKA-1 prevents the binding to E2F transcription factors, allowing G1 to S phase transition to operate (PubMed-18064404, PubMed-21444209). Forms a stable complex with E2FA that functions in maintaining cell proliferation through repression of cell differentiation (PubMed-22307083). Plays a central role in the mechanism controlling meristem cell differentia [...] (1013 aa)
     
  0.985
CDC20.2
Cell division cycle 20.2; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle (447 aa)
     
  0.985
AT1G07270
Cell division control, Cdc6; May be involved in the initiation of DNA replication (505 aa)
     
  0.984
AT5G27945
Cell division cycle 20, cofactor of APC complex; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle (428 aa)
     
  0.983
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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