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CYCA3;4 protein (Arabidopsis thaliana) - STRING interaction network
"CYCA3;4" - CYCLIN A3 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CYCA3;4CYCLIN A3;4 (CYCA3;4); Its function is described as cyclin-dependent protein kinase regulator activity; Involved in regulation of cell cycle; Located in nucleus; Expressed in 20 plant structures; Expressed during 11 growth stages; Contains the following InterPro domains- Cyclin, C-terminal (InterPro-IPR004367), G2/mitotic-specific cyclin A (InterPro-IPR015453), Cyclin-like (InterPro-IPR011028), Cyclin-related (InterPro-IPR013763), Cyclin, N-terminal (InterPro-IPR006671), Cyclin, A/B/D/E (InterPro-IPR014400), Cyclin (InterPro-IPR006670); BEST Arabidopsis thaliana protein match is- cycli [...] (370 aa)    
Predicted Functional Partners:
CDC2
A-type cyclin-dependent kinase. Together with its specific inhibitor, the Kip-related protein, KRP2 they regulate the mitosis-to-endocycle transition during leaf development. Dominant negative mutations abolish cell division. Loss of function phenotype has reduced fertility with failure to transmit via pollen. Pollen development is arrested at the second mitotic division. Expression is regulated by environmental and chemical signals. Part of the promoter is responsible for expression in trichomes. Functions as a positive regulator of cell proliferation during development of the male [...] (294 aa)
     
  0.999
AT4G24820
26S proteasome, regulatory subunit Rpn7;Proteasome component (PCI) domain; Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (387 aa)
       
    0.999
CKS2
Cyclin-dependent kinases regulatory subunit 2; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function (83 aa)
     
 
  0.998
CKS1
Catalytic subunit of cyclin dependent kinase 1. physically interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle; Belongs to the CKS family (87 aa)
     
 
  0.997
MCM5
Minichromosome maintenance (MCM2/3/5) family protein; Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin (727 aa)
     
  0.995
AT4G25550
Cleavage/polyadenylation specificity factor, 25kDa subunit; Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3’-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3’-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5’-UGUA-3’ elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export; Belongs to the Nudix hydrolase family. CPSF [...] (200 aa)
     
      0.995
AT4G14310
Transducin/WD40 repeat-like superfamily protein; Might be involved in division plane determination (920 aa)
     
      0.995
CEL3
Endoglucanase 9; Cellulase 3 (CEL3); Its function is described as hydrolase activity, hydrolyzing O-glycosyl compounds, catalytic activity; Involved in carbohydrate metabolic process; Located in cell wall, plasma membrane, plant-type cell wall; Expressed in 7 plant structures; Expressed during L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; Contains the following InterPro domains- Six-hairpin glycosidase (InterPro-IPR012341), Six-hairpin glycosidase-like (InterPro-IPR008928), Glycoside hydrolase, family 9, active site (InterPro-I [...] (484 aa)
       
      0.995
MCM2
Minichromosome maintenance (MCM2/3/5) family protein; Probable component of the MCM2-7 complex (MCM complex) that may function as a DNA helicase and which is essential to undergo a single round of replication initiation and elongation per cell cycle in eukaryotic cells. May play a crucial role in the control of de-differentiation and cell proliferation processes required for lateral root formation. Is essential for embryo development. Is involved in the geminivirus mungbean yellow mosaic virus (MYMV) DNA replication, presumably in conjunction with other host factors (936 aa)
     
  0.993
CDC6
Cell division control protein 6 homolog; May be involved in the initiation of DNA replication. May play a role in endoreduplication. Could act as one of the factors that contributes to maintain endoreduplication competence; Belongs to the CDC6/cdc18 family (539 aa)
     
  0.988
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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