• Version:
  • 11.0 (preview - - version 10.5 still available here)
DGAT3 protein (Arabidopsis thaliana) - STRING interaction network
"DGAT3" - Diacylglycerol O-acyltransferase 3, cytosolic in Arabidopsis thaliana
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
Your Input:
Gene Fusion
DGAT3Diacylglycerol O-acyltransferase 3, cytosolic; Involved in triacylglycerol (TAG) biosynthesis in cytosol. Catalyzes the acylation of the sn-3 hydroxy group of sn- 1,2-diacylglycerol using acyl-CoA. Preferentially uses linolenoyl- CoA as substrate and to a lesser extent linoleoyl-CoA. May contribute to the active recycling of linoleate and linolenate into TAG when seed oil breakdown is blocked (285 aa)    
Predicted Functional Partners:
Diacylglycerol acyltransferase family; Involved in triacylglycerol (TAG) synthesis. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Can use oleoyl- CoA, linoleoyl-CoA and linolenoyl-CoA as substrates. Has substrate preference for linolenoyl-CoA or oleoyl-CoA compared to linoleoyl- CoA (314 aa)
Membrane bound O-acyl transferase (MBOAT) family protein; Major contributor to triacylglycerol (TAG) synthesis and oil accumulation in seeds. Catalyzes the acylation of the sn-3 hydroxy group of sn-1,2-diacylglycerol using acyl-CoA. Can use palmitoyl-CoA and oleoyl-CoA as substrates. Can use oleoyl-CoA and linoleoyl-CoA as substrates. Has substrate preference for oleoyl-CoA compared to linoleoyl-CoA. Has complementary functions with PDAT1 that are essential for triacylglycerol synthesis and normal development of both seeds and pollen (520 aa)
Phospholipid-diacylglycerol acyltransferase 1; Triacylglycerol formation by an acyl-CoA independent pathway. The enzyme preferentially transfers acyl groups from the sn-2 position of a phospholipid to diacylglycerol, thus forming an sn-1-lysophospholipid. Involved in epoxy and hydroxy fatty acid accumulation in seeds. Has complementary functions with DAG1 that are essential for triacylglycerol synthesis and normal development of both seeds and pollen (671 aa)
Uncharacterized protein At2g23390; Contains the following InterPro domains- Protein of unknown function DUF482 (InterPro-IPR007434), Acyl-CoA N-acyltransferase (InterPro-IPR016181); Has 2165 Blast hits to 2163 proteins in 543 species- Archae - 0; Bacteria - 1044; Metazoa - 0; Fungi - 0; Plants - 33; Viruses - 0; Other Eukaryotes - 1088 (source- NCBI BLink) (469 aa)
MATE efflux family protein; Functions as a multidrug and toxin extrusion transporter that negatively regulates plant disease resistance. Plays an important role in maintaining normal plant architecture, possibly by regulating local auxin biosynthesis. May act as a negative regulator of hypocotyl cell elongation in the light (532 aa)
Uncharacterized protein At3g56360; Unknown protein; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in chloroplast; Expressed in 24 plant structures; Expressed during 15 growth stages; BEST Arabidopsis thaliana protein match is- unknown protein (TAIR-AT5G05250.1); Has 45 Blast hits to 45 proteins in 13 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 45; Viruses - 0; Other Eukaryotes - 0 (source- NCBI BLink) (233 aa)
HXXXD-type acyl-transferase family protein; Encodes PERMEABLE LEAVES3 (PEL3), a putative acyl-transferase. Mutation in this locus results in altered trichome phenotype (trcichomes become tangled during leaf expansion). Additional phenotype includes altered cuticle layer (484 aa)
O-acyltransferase (WSD1-like) family protein; Encodes a bifunctional enzyme, wax ester synthase (WS) and diacylglycerol acyltransferase (DGAT). In vitro assay indicated a ratio of 10.9 between its WS and DGAT activities. Both mutant and in vivo expression/analysis in yeast studies indicated a role in wax biosynthesis; In the N-terminal section; belongs to the long-chain O-acyltransferase family (481 aa)
Putative phospholipid-diacylglycerol acyltransferase 2; Lecithin-cholesterol acyltransferase family protein; Its function is described as phosphatidylcholine-sterol O-acyltransferase activity; Involved in lipid metabolic process; Located in cellular_component unknown; Contains the following InterPro domains- Lecithin-cholesterol acyltransferase (InterPro-IPR003386); BEST Arabidopsis thaliana protein match is- phospholipid-diacylglycerol acyltransferase (TAIR-AT5G13640.1); Has 743 Blast hits to 672 proteins in 235 species- Archae - 0; Bacteria - 21; Metazoa - 207; Fungi - 173; Plants - [...] (665 aa)
Phospholipid/glycerol acyltransferase family protein; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate. The enzyme from chilling-resistant plants discriminates against non-fluid palmitic acid and selects oleic acid whereas the enzyme from sensitive plants accepts both fatty acids. This is an oleate-selective acyltransferase (459 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (8%) [HD]