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PEX3 protein (Arabidopsis thaliana) - STRING interaction network
"PEX3" - Peroxisome biogenesis protein 3-2 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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PEX3Peroxisome biogenesis protein 3-2; Involved in morphology determination of peroxisomes, but not in import of peroxisomal matrix proteins. May act as a docking factor for PEX19 and be necessary for the import of peroxisomal membrane proteins in the peroxisomes (400 aa)    
Predicted Functional Partners:
ABCD1
ABC transporter D family member 1; Contributes to the transport of fatty acids and their derivatives (acyl CoAs) across the peroxisomal membrane. Provides acetate to the glyoxylate cycle in developing seedlings. Involved in pollen tube elongation, ovule fertilization, and seeds germination after imbibition (controls the switch between the opposing developmental programs of dormancy and germination), probably by promoting beta-oxidation of storage lipids during gluconeogenesis. Required for biosynthesis of jasmonic acid and conversion of indole butyric acid to indole acetic acid. Confer [...] (1352 aa)
     
  0.999
PEX12
Peroxisome biogenesis protein 12; Required for peroxisome biogenesis and for PTS1- and PTS2-dependent protein import into peroxisomes. Essential for the peroxisomal targeting of PEX7. Required for the export/release of receptors on the peroxisome membrane. Acts as an E3 ubiquitin- protein ligase involved in monoubiquitination of PEX5 (393 aa)
     
 
  0.989
PEX5
Peroxisome biogenesis protein 5; Encodes the peroxisomal targeting signal type 1 receptor that facilitates peroxisomal protein translocation. It recognizes proteins with the PTS1 consensus sequence (tripeptide SKL or a conserved variant) at the extreme C terminus. The protein has several domains, including C-terminal tetratricopeptide repeat motifs which act in binding the C-terminal "SKL" targeting signal. The mechanism of transport has been worked out in other organisms- The receptor recognizes and binds cytosolic PTS1-containing proteins. The PEX5-PTS1 complex binds a PEX14/PEX1 [...] (728 aa)
     
 
  0.973
SSE1
Encodes a protein with similarity to yeast Pep16p, a membrane localized protein involved in peroxisome assembly and protein-trafficking. SSE1 mutant seeds do not accumulate oils and dessicated seeds have a shrunken appearance. Involved in protein and oil body biogenesis. SSE is expressed during seed development, reaching the highest peak in mature siliques. Expression in leaves and roots is low compared to cotyledons and flowers. Located in peroxisomes and endoplasmic reticulum. Homologous to the peroxin PEX16 and complements the pex16 mutants of the yeast Yarrowia lipolytica (367 aa)
     
 
  0.973
PUP7
Probable purine permease 7; Member of a family of proteins related to PUP1, a purine transporter. May be involved in the transport of purine and purine derivatives such as cytokinins, across the plasma membrane (390 aa)
           
  0.953
PEX19-2
Peroxisome biogenesis protein 19-2; Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins. Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer; Belongs to the peroxin-19 family (245 aa)
     
 
  0.943
PEX19-1
Peroxisome biogenesis protein 19-1; Contributes to morphology determination of peroxisomes, but not to import of peroxisomal matrix proteins. Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Required for transport of APEM9 to peroxisome membranes. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer; Belongs to the peroxin-19 family (248 aa)
     
 
  0.943
AT5G60335
Hydroxyacyl-thioester dehydratase type-like protein; Thioesterase superfamily protein; Its function is described as oxidoreductase activity; Involved in metabolic process; Contains the following InterPro domains- MaoC-like dehydratase (InterPro-IPR002539) (166 aa)
     
   
  0.925
ECH2
Encodes a monofunctional enoyl-CoA hydratase 2, involved in the degradation of even cis-unsaturated fatty acids, gene expression is enhanced during the first 2 days of germination, as well as in senescent leaves (309 aa)
     
   
  0.925
ABCD2
ABC transporter family protein; Its function is described as ATPase activity, coupled to transmembrane movement of substances; Involved in transport, transmembrane transport; Located in chloroplast; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- ATPase, AAA+ type, core (InterPro-IPR003593), ABC transporter, N-terminal (InterPro-IPR010509), ABC transporter-like (InterPro-IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro-IPR011527), ABC transporter integral membrane type 1 (InterPro-IPR017940), ABC transport [...] (706 aa)
     
 
  0.922
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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