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SCD1 protein (Arabidopsis thaliana) - STRING interaction network
"SCD1" - Stomatal cytokinesis defective / SCD1 protein in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
protein homology
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Gene Fusion
SCD1Stomatal cytokinesis defective / SCD1 protein (SCD1); Encodes soluble protein containing N-terminal DENN domain and eight C-terminal WD-40 repeats. Involved in cytokinesis of guard mother cells and leaf epidermal cells. The overall growth and development of mutant plants is severely affected, they are smaller than wt, with defects in seedling development, leaf expansion and flower morphology which renders the mutant conditionally sterile (1187 aa)    
Predicted Functional Partners:
Coiled-coil domain-containing protein SCD2; Involved in growth and development through its role in cytokinesis and polarized cell expansion. Required for plasma membrane internalization. May function in clathrin-mediated membrane trafficking, including plasma membrane endocytosis, essential to both cytokinesis and cell expansion (577 aa)
IBR domain containing protein; Its function is described as zinc ion binding; Involved in biological_process unknown; Located in cellular_component unknown; Expressed in sperm cell; Contains the following InterPro domains- Zinc finger, RING-type (InterPro-IPR001841), Zinc finger, C6HC-type (InterPro-IPR002867); BEST Arabidopsis thaliana protein match is- RING/U-box superfamily protein (TAIR-AT5G37560.1); Has 87308 Blast hits to 18333 proteins in 957 species- Archae - 370; Bacteria - 41195; Metazoa - 14245; Fungi - 8075; Plants - 4321; Viruses - 1278; Other Eukaryotes - 17824 (source- N [...] (468 aa)
E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to CDC48 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family (1873 aa)
Probable NEDD8-conjugating enzyme Ubc12-like; Accepts the ubiquitin-like protein NEDD8/RUB1 from the ECR1-AXR1 E1 complex and catalyzes its covalent attachment to other proteins (185 aa)
HEAT repeat ;HECT-domain (ubiquitin-transferase); Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the repression of endoreduplication process and the cell morphogenesis in the trichomes (1888 aa)
E3 ubiquitin-protein ligase PRT6; Ubiquitin ligase protein which is a component of the N- end rule pathway with the arginyltransferases ATE1 and ATE2. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Does not participate in degradation of proteins with N-terminal Phe or Leu. The N-end rule pathway regulates seed after-ripening, seedling sugar sensitivity, seedling lipid breakdown, and abscisic acid (ABA) sensitivity of germination. The end-rule pathway re [...] (2006 aa)
Auxin transport protein (BIG); Required for auxin efflux and polar auxin transport (PAT) influencing auxin-mediated developmental responses (e.g. cell elongation, apical dominance, lateral root production, inflorescence architecture, general growth and development). Controls the elongation of the pedicels and stem internodes through auxin action. Involved in the expression modulation of light-regulated genes. Represses CAB1 and CAB3 genes expression in etiolated seedlings. Confers sensitivity to the auxin transport inhibitors N-1-naphthylphthalamic acid (NPA), 2-carboxyphenyl-3- phenyl [...] (5098 aa)
Cyclin-dependent protein kinase 3;2 (CYCA3;2); Contains the following InterPro domains- Cyclin, C-terminal (InterPro-IPR004367), Cyclin (InterPro-IPR006670), G2/mitotic-specific cyclin A (InterPro-IPR015453), Cyclin-like (InterPro-IPR011028), Cyclin-related (InterPro-IPR013763), Cyclin, N-terminal (InterPro-IPR006671), Cyclin, A/B/D/E (InterPro-IPR014400); BEST Arabidopsis thaliana protein match is- CYCLIN A3;4 (TAIR-AT1G47230.1); Has 4323 Blast hits to 4316 proteins in 367 species- Archae - 0; Bacteria - 0; Metazoa - 1987; Fungi - 532; Plants - 1111; Viruses - 34; Other Eukaryotes - 6 [...] (372 aa)
Encodes a ubiquitin-protein ligase-like protein containing a HECT domain. There are six other HECT-domain UPLs in Arabidopsis (3658 aa)
Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined. Mutant is able to revert the constitutive defense responses phenotype of snc1, which indicates the gene is involved in defense response. It also indicates that ubiquitination plays a role in plant defense signalling (1080 aa)
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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