| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AT1G28060 | AT1G49590 | AT1G28060.1 | AT1G49590.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | 0.974 |
| AT1G28060 | AT2G40650 | AT1G28060.1 | AT2G40650.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | Pre-mRNA-splicing factor 38; Probably required for the first pre-mRNA cleavage reaction catalyzed by the spliceosome | 0.894 |
| AT1G28060 | AT2G42270 | AT1G28060.1 | AT2G42270.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | U5 small nuclear ribonucleoprotein helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly | 0.884 |
| AT1G28060 | AT3G05760 | AT1G28060.1 | AT3G05760.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | C2H2 and C2HC zinc fingers superfamily protein; Its function is described as zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in intracellular; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Zinc finger, C2H2-like (InterPro-IPR015880), Zinc finger, U1-type (InterPro-IPR003604), Zinc finger, double-stranded RNA binding (InterPro-IPR022755); Has 718 Blast hits to 676 proteins in 204 species- Archae - 2; Bacteria - 14; Metazoa - 302; Fungi - 150; Plants - 49; Viruses - 2; Other Eukaryotes [...] | 0.929 |
| AT1G28060 | AT5G44500 | AT1G28060.1 | AT5G44500.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | Small nuclear ribonucleoprotein family protein; Its function is described as molecular_function unknown; Located in nucleolus, nucleus, small nucleolar ribonucleoprotein complex; Expressed in 7 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Like-Sm ribonucleoprotein (LSM) domain (InterPro-IPR001163), Small ribonucleoprotein associated, SmB/SmN (InterPro-IPR017131), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro-IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro-IPR010920); BEST Arabidopsis thalia [...] | 0.843 |
| AT1G28060 | AT5G64270 | AT1G28060.1 | AT5G64270.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | Splicing factor, putative; Its function is described as binding; Involved in mRNA processing; Located in chloroplast; Expressed in 26 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Armadillo-like helical (InterPro-IPR011989), Splicing factor 3B subunit 1 (InterPro-IPR015016), HEAT, type 2 (InterPro-IPR021133), Armadillo-type fold (InterPro-IPR016024); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source [...] | 0.971 |
| AT1G28060 | SMU1 | AT1G28060.1 | AT1G73720.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | Transducin family protein / WD-40 repeat family protein; Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development. Required for proper accumulation of SMU2 | 0.858 |
| AT1G28060 | U2B' | AT1G28060.1 | AT2G30260.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | U2 small nuclear ribonucleoprotein B’; Encodes U2B", which is a component of the U2 snRNP complex. Its precise role in pre-mRNA splicing is still unknown. It has been suggested that U2B0 may not be required for the splicing reaction itself but may have a role in U2 snRNP biogenesis. Deletion analysis of the U2B0 gene fusion has identified the N-terminal RNP-80 motif as sufficient for localization to the coiled body and the nucleus | 0.936 |
| AT1G28060 | emb1220 | AT1G28060.1 | AT1G60170.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | pre-mRNA processing ribonucleoprotein binding region-containing protein; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). Functions in association with STA1 and ZOP1 in spliceosome dynamics and pre-mRNA splicing. Required for transcriptional regulation and pre-mRNA splicing of cold-responsive genes, such as LTI78/RD29A, KIN2/COR6.6 or COR15A, especially under cold stress. May play a role in stress response. Involved in transcriptional gene silencing of endogenous transposable eleme [...] | 0.987 |
| AT1G28060 | emb1507 | AT1G28060.1 | AT1G20960.1 | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly | 0.896 |
| AT1G49590 | AT1G28060 | AT1G49590.1 | AT1G28060.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci | 0.974 |
| AT1G49590 | AT2G40650 | AT1G49590.1 | AT2G40650.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | Pre-mRNA-splicing factor 38; Probably required for the first pre-mRNA cleavage reaction catalyzed by the spliceosome | 0.890 |
| AT1G49590 | AT2G42270 | AT1G49590.1 | AT2G42270.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | U5 small nuclear ribonucleoprotein helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly | 0.886 |
| AT1G49590 | AT3G05760 | AT1G49590.1 | AT3G05760.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | C2H2 and C2HC zinc fingers superfamily protein; Its function is described as zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in intracellular; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Zinc finger, C2H2-like (InterPro-IPR015880), Zinc finger, U1-type (InterPro-IPR003604), Zinc finger, double-stranded RNA binding (InterPro-IPR022755); Has 718 Blast hits to 676 proteins in 204 species- Archae - 2; Bacteria - 14; Metazoa - 302; Fungi - 150; Plants - 49; Viruses - 2; Other Eukaryotes [...] | 0.939 |
| AT1G49590 | AT5G44500 | AT1G49590.1 | AT5G44500.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | Small nuclear ribonucleoprotein family protein; Its function is described as molecular_function unknown; Located in nucleolus, nucleus, small nucleolar ribonucleoprotein complex; Expressed in 7 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Like-Sm ribonucleoprotein (LSM) domain (InterPro-IPR001163), Small ribonucleoprotein associated, SmB/SmN (InterPro-IPR017131), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro-IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro-IPR010920); BEST Arabidopsis thalia [...] | 0.890 |
| AT1G49590 | AT5G64270 | AT1G49590.1 | AT5G64270.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | Splicing factor, putative; Its function is described as binding; Involved in mRNA processing; Located in chloroplast; Expressed in 26 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Armadillo-like helical (InterPro-IPR011989), Splicing factor 3B subunit 1 (InterPro-IPR015016), HEAT, type 2 (InterPro-IPR021133), Armadillo-type fold (InterPro-IPR016024); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source [...] | 0.981 |
| AT1G49590 | SMU1 | AT1G49590.1 | AT1G73720.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | Transducin family protein / WD-40 repeat family protein; Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development. Required for proper accumulation of SMU2 | 0.894 |
| AT1G49590 | U2B' | AT1G49590.1 | AT2G30260.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | U2 small nuclear ribonucleoprotein B’; Encodes U2B", which is a component of the U2 snRNP complex. Its precise role in pre-mRNA splicing is still unknown. It has been suggested that U2B0 may not be required for the splicing reaction itself but may have a role in U2 snRNP biogenesis. Deletion analysis of the U2B0 gene fusion has identified the N-terminal RNP-80 motif as sufficient for localization to the coiled body and the nucleus | 0.952 |
| AT1G49590 | emb1220 | AT1G49590.1 | AT1G60170.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | pre-mRNA processing ribonucleoprotein binding region-containing protein; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). Functions in association with STA1 and ZOP1 in spliceosome dynamics and pre-mRNA splicing. Required for transcriptional regulation and pre-mRNA splicing of cold-responsive genes, such as LTI78/RD29A, KIN2/COR6.6 or COR15A, especially under cold stress. May play a role in stress response. Involved in transcriptional gene silencing of endogenous transposable eleme [...] | 0.986 |
| AT1G49590 | emb1507 | AT1G49590.1 | AT1G20960.1 | C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II | U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly | 0.886 |
