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AT1G49590 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G49590" - C2H2 and C2HC zinc fingers superfamily protein in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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AT1G49590C2H2 and C2HC zinc fingers superfamily protein; Nucleic acid-binding protein that promotes Pol IV- dependent small interfering RNA (siRNA) accumulation, DNA methylation and transcriptional silencing. May possess both RNA- directed DNA methylation (RdDM)-dependent and -independent roles in transcriptional silencing. Acts as a pre-mRNA splicing factor that associates with several typical components of the splicing machinery as well as with Pol II (242 aa)    
Predicted Functional Partners:
emb1220
pre-mRNA processing ribonucleoprotein binding region-containing protein; Involved in pre-mRNA splicing. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome (By similarity). Functions in association with STA1 and ZOP1 in spliceosome dynamics and pre-mRNA splicing. Required for transcriptional regulation and pre-mRNA splicing of cold-responsive genes, such as LTI78/RD29A, KIN2/COR6.6 or COR15A, especially under cold stress. May play a role in stress response. Involved in transcriptional gene silencing of endogenous transposable eleme [...] (485 aa)
       
 
  0.986
AT5G64270
Splicing factor, putative; Its function is described as binding; Involved in mRNA processing; Located in chloroplast; Expressed in 26 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- HEAT (InterPro-IPR000357), Armadillo-like helical (InterPro-IPR011989), Splicing factor 3B subunit 1 (InterPro-IPR015016), HEAT, type 2 (InterPro-IPR021133), Armadillo-type fold (InterPro-IPR016024); Has 1807 Blast hits to 1807 proteins in 277 species- Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source [...] (1269 aa)
     
 
  0.981
AT1G28060
Pre-mRNA-splicing factor 3; Functions in the RNA-directed DNA methylation (RdDM) pathway. Acts as a pre-mRNA splicing factor, likely by affecting Pol V transcripts. Affects DNA methylation of transposable elements (TEs) and preferentially influences NRPD1- and ROS1- targeted loci (786 aa)
       
 
  0.974
U2B'
U2 small nuclear ribonucleoprotein B’; Encodes U2B", which is a component of the U2 snRNP complex. Its precise role in pre-mRNA splicing is still unknown. It has been suggested that U2B0 may not be required for the splicing reaction itself but may have a role in U2 snRNP biogenesis. Deletion analysis of the U2B0 gene fusion has identified the N-terminal RNP-80 motif as sufficient for localization to the coiled body and the nucleus (232 aa)
       
 
  0.952
AT3G05760
C2H2 and C2HC zinc fingers superfamily protein; Its function is described as zinc ion binding, nucleic acid binding; Involved in biological_process unknown; Located in intracellular; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains- Zinc finger, C2H2-like (InterPro-IPR015880), Zinc finger, U1-type (InterPro-IPR003604), Zinc finger, double-stranded RNA binding (InterPro-IPR022755); Has 718 Blast hits to 676 proteins in 204 species- Archae - 2; Bacteria - 14; Metazoa - 302; Fungi - 150; Plants - 49; Viruses - 2; Other Eukaryotes [...] (202 aa)
     
 
  0.939
SMU1
Transducin family protein / WD-40 repeat family protein; Auxiliary spliceosomal protein involved in splicing of specific pre-mRNAs that affect multiple aspects of development. Required for proper accumulation of SMU2 (511 aa)
     
 
  0.894
AT2G40650
Pre-mRNA-splicing factor 38; Probably required for the first pre-mRNA cleavage reaction catalyzed by the spliceosome (355 aa)
     
 
  0.890
AT5G44500
Small nuclear ribonucleoprotein family protein; Its function is described as molecular_function unknown; Located in nucleolus, nucleus, small nucleolar ribonucleoprotein complex; Expressed in 7 plant structures; Expressed during 6 growth stages; Contains the following InterPro domains- Like-Sm ribonucleoprotein (LSM) domain (InterPro-IPR001163), Small ribonucleoprotein associated, SmB/SmN (InterPro-IPR017131), Like-Sm ribonucleoprotein (LSM) domain, eukaryotic/archaea-type (InterPro-IPR006649), Like-Sm ribonucleoprotein (LSM)-related domain (InterPro-IPR010920); BEST Arabidopsis thalia [...] (254 aa)
     
 
  0.890
AT2G42270
U5 small nuclear ribonucleoprotein helicase; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly (2172 aa)
       
 
  0.886
emb1507
U5 small nuclear ribonucleoprotein helicase, putative; RNA helicase that plays an essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes. Involved in spliceosome assembly, activation and disassembly (2171 aa)
       
 
  0.886
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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