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ICK5 protein (Arabidopsis thaliana) - STRING interaction network
"ICK5" - Cyclin-dependent kinase inhibitor 7 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ICK5Cyclin-dependent kinase inhibitor 7; Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. May target specifically CDKA-1 (195 aa)    
Predicted Functional Partners:
CDC2
Cell division control 2; Involved in the control of the cell cycle. Essential for both G1/S and G2/M (mitosis) phase transitions. Functions in cell morphogenesis as well as cell proliferation. Required for cell division (entry into mitosis) of the generative cell in male gametogenesis (294 aa)
       
 
  0.998
CYCD2;1
Cyclin D2;1; Acts on the G1 phase of the cell cycle to control cell division rate in both shoot and root meristems. The complex formed with CDKA-1 phosphorylates plant retinoblastoma protein (362 aa)
       
 
  0.998
CYCD5;1
Cyclin d5;1 (323 aa)
       
 
  0.998
CKS1
Cyclin-dependent kinase-subunit 1; Associates with cyclin-dependent kinases (CDKs) and plays an essential role in the regulation of the cell cycle that affects plant growth rate. May inhibit both the G1/S and G2/M phases (87 aa)
       
 
  0.998
CYCD4;1
CYCLIN D4;1; May activate cell cycle in the root apical meristem (RAM) and promote embryonic root (radicle) protrusion (318 aa)
       
 
  0.997
CYCD4;2
Cyclin d4;2; May promote cell division (298 aa)
       
 
  0.997
CYCD6;1
Cyclin D6-1 (302 aa)
       
 
  0.996
IMPA-2
Importin alpha isoform 2; Binds to conventional NLS motifs and mediates nuclear protein import across the nuclear envelope (By similarity). Acts as cellular receptor for the nuclear import of the virD2 protein of Agrobacterium, but is not essential for Agrobacterium-mediated root transformation (PubMed-18836040) (535 aa)
       
      0.995
FBL17
F-box/LRR-repeat protein 17; Essential protein for male fertility. Component of the SCF(ASK-cullin-F-box) E3 ubiquitin ligase complex SCF(FBL17), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Enables the switch in cell cycle control leading to male germ cell lineage formation from microspores after meiosis. Targets CDKA-1 inhibitors the degradation specifically in male germ cells (e.g. KRP6 and KRP7) and thus enables CDKA-1 activation and germ cell S-phase progression. Promotes twin sperm cell production and double fertilization (593 aa)
       
 
  0.944
KRP2
KIP-related protein 2; Binds and inhibits CYCD2-1/CDKA-1 complex kinase activity. Regulates cell division which is crucial for plant growth, development and morphogenesis. May regulate early lateral root initiation by blocking the G1/S phase transition. Controls the mitosis-to-endocycle transition and the onset of the endoreduplication cycle during leaf development through inhibition of mitotic CDKA-1 kinase complexes. Specifically targets CDKA-1 (209 aa)
     
   
  0.874
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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