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Erv1 protein (Arabidopsis thaliana) - STRING interaction network
"Erv1" - FAD-linked sulfhydryl oxidase ERV1 in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Erv1FAD-linked sulfhydryl oxidase ERV1; FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation (By similarity). Oxidizes thioredoxin in vitro. Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space. Forms a redox cycle with MIA40 that involves a disulfide relay system. Important for maintaining the cysteine residues in MIA40 in an oxidized state (By similarity) (191 aa)    
Predicted Functional Partners:
MIA40
Mitochondrial intermembrane space import and assembly protein 40 homolog; Required for the import and folding of small cysteine- containing proteins in the mitochondrial intermembrane space (Probable). Involved in the mitochondrial oxidative folding of the copper-zinc superoxide dismutase CSD1, the copper chaperone for superoxide dismutase CCS, and subunits of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I). Involved in the peroxisomal oxidative folding of the copper-zinc superoxide dismutase CSD3, and the fatty acid beta-oxidation multifunctional protein AIM1 (162 aa)
     
 
  0.994
TIM9
Mitochondrial import inner membrane translocase subunit TIM9; Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity) (93 aa)
       
 
  0.977
TIM10
Encodes a small zinc finger-like protein that is a component of the mitochondrial protein import apparatus (107 aa)
     
 
  0.975
TIM50
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; Essential component of the TIM17-23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane; Belongs to the TIM50 family (376 aa)
     
   
  0.959
TIM13
Mitochondrial import inner membrane translocase subunit TIM13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex mediates the import of some protein [...] (87 aa)
     
   
  0.940
ERO1
Endoplasmic reticulum oxidoreductins 1; Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on PDI to transfer oxidizing equivalent. Does not oxidize all PDI related proteins, suggesting that it can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a signific [...] (469 aa)
       
 
  0.932
AT1G10865
Cytochrome C oxidase assembly factor; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in cellular_component unknown; Contains the following InterPro domains- Cytochrome c oxidase assembly protein PET191, N-terminal (InterPro-IPR018793); Has 241 Blast hits to 241 proteins in 124 species- Archae - 0; Bacteria - 0; Metazoa - 100; Fungi - 94; Plants - 38; Viruses - 0; Other Eukaryotes - 9 (source- NCBI BLink) (71 aa)
           
  0.921
TOM40
Translocase of the outer mitochondrial membrane 40; Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore. Directly involved in the pore formation; Belongs to the Tom40 family (309 aa)
     
   
  0.919
COX17
Encodes protein similar to yeast COX17, a copper-binding protein that mediates the delivery of Cu to the mitochondria for the assembly of a functional cytochrome oxidase complex (74 aa)
     
 
  0.910
TIM8
Mitochondrial import inner membrane translocase subunit TIM8; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIM8-TIM13 complex mediates the import of some proteins [...] (77 aa)
           
  0.908
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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