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SIRB protein (Arabidopsis thaliana) - STRING interaction network
"SIRB" - Sirohydrochlorin ferrochelatase, chloroplastic in Arabidopsis thaliana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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SIRBSirohydrochlorin ferrochelatase, chloroplastic; Chelates iron to the siroheme precursor. Catalyzes the last step of the siroheme biosynthesis. Unlike its counterparts in bacteria, contains an [Fe-S] cluster which is not involved directly in the enzymatic reaction, but may play regulatory role in iron, sulfur and tetrapyrrole metabolism. The [Fe-S] cluster is required for normal plant growth (225 aa)    
Predicted Functional Partners:
AT1G71500
Uncharacterized protein At1g71500/F26A9_12; Rieske (2Fe-2S) domain-containing protein; Its function is described as oxidoreductase activity, 2 iron, 2 sulfur cluster binding; Involved in oxidation reduction; Located in chloroplast thylakoid membrane, chloroplast, chloroplast envelope; Expressed in 23 plant structures; Expressed during 14 growth stages; Contains the following InterPro domains- Rieske [2Fe-2S] iron-sulphur domain (InterPro-IPR017941); Has 295 Blast hits to 295 proteins in 102 species- Archae - 0; Bacteria - 166; Metazoa - 0; Fungi - 0; Plants - 94; Viruses - 0; Other Euk [...] (287 aa)
   
   
  0.935
AT2G04700
Ferredoxin thioredoxin reductase catalytic beta chain family protein; Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin (146 aa)
     
   
  0.895
UPM1
Encodes a urophorphyrin III methylase that catalyzes S-adenosyl-L-methionine-dependent transmethylation in a multistep process involving the formation of a covalently linked complex with S-adenosyl-L-methionine; Belongs to the precorrin methyltransferase family (369 aa)
   
   
  0.889
NIR1
Ferredoxin--nitrite reductase, chloroplastic; Involved in the second step of nitrate assimilation. Its expression is induced by nitrate; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (586 aa)
   
   
  0.869
SIR
Assimilatory sulfite reductase (ferredoxin), chloroplastic; Essential protein with sulfite reductase activity required in assimilatory sulfate reduction pathway during both primary and secondary metabolism and thus involved in development and growth; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (642 aa)
   
   
  0.822
HEMD
Uroporphyrinogen-III synthase, chloroplastic; Encodes a uroporphyrinogen-III synthase involved in tetrapyrrole biosynthesis. The protein localizes to the chloroplast. Member of the plant-specific DUF724 protein family. Arabidopsis has 10 DUF724 proteins. Loss of function mutant has a WT phenotype (321 aa)
   
   
  0.815
GUN5
Magnesium-chelatase subunit ChlH, chloroplastic; Multifunctional protein involved in chlorophyll synthesis, plastid-to-nucleus retrograde signaling and abscisic acid (ABA) perception. In chlorophyll synthesis, catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX. The reaction takes place in two steps, with an ATP-dependent activation followed by an ATP-dependent chelation step. In addition to its function in the Mg-chelatase enzyme, is required for the plastid-to-nucleus retrograde signaling. The plastid-to-nucleus signal plays an important rol [...] (1381 aa)
         
  0.759
AT5G13440
Cytochrome b-c1 complex subunit Rieske-2, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (274 aa)
           
  0.709
AT5G14550
Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein; Contains the following InterPro domains- Core-2/I-Branching enzyme (InterPro-IPR021141); BEST Arabidopsis thaliana protein match is- Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein (TAIR-AT1G11940.1); Has 574 Blast hits to 572 proteins in 18 species- Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 548; Viruses - 0; Other Eukaryotes - 26 (source- NCBI BLink) (377 aa)
           
  0.697
AT5G11010
Pre-mRNA cleavage complex II protein family; Polynucleotide 5’-kinase involved in rRNA processing (368 aa)
           
  0.697
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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