STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
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[Homology]
Score
DRP4CDynamin related protein 4C; Putative microtubule-associated force-producing protein, able to bind and hydrolyze GTP (669 aa)    
Predicted Functional Partners:
Cand1
Uncharacterized protein At1g57680; Its function is described as molecular_function unknown; Involved in biological_process unknown; Located in endomembrane system; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: Uncharacterised conserved protein UCP031277 (InterPro:IPR016971); Has 70 Blast hits to 70 proteins in 19 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 0; Plants - 66; Viruses - 0; Other Eukaryotes - 3 (source: NCBI BLink)
      
 0.903
AT2G20050
Protein phosphatase 2C and cyclic nucleotide-binding/kinase domain-containing protein; Protein serine/threonine phosphatases;protein kinases;catalytics;cAMP-dependent protein kinase regulators;ATP binding;protein serine/threonine phosphatases; Its function is described as cAMP-dependent protein kinase regulator activity, protein kinase activity, protein serine/threonine phosphatase activity, catalytic activity, ATP binding; Involved in protein amino acid phosphorylation, protein amino acid dephosphorylation, N-terminal protein myristoylation, regulation of protein amino acid phosphoryl [...]
   
 
 0.863
AT1G60160
Potassium transporter family protein; Putative potassium transporter
      
 0.838
ATG18H
Homolog of yeast autophagy 18 (ATG18) H; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Required for autophagy (By similarity); Belongs to the WD repeat SVP1 family
   
  
 0.769
SFR2
Galactolipid galactosyltransferase SFR2, chloroplastic; Glycosyl hydrolase family protein acting primarily as a highly specific galactosyltransferase. Synthesizes digalactosyldiacylglycerol from monogalactosyldiacylglycerol in the absence of UDP-galactose in vitro. Hydrolyzes o- and p-nitrophenyl beta-D- glucoside in vitro. Plays a role in freezing tolerance. May play a role in chloroplast protection
      
 0.726
AT1G20760
Calcium-binding EF hand family protein; Its function is described as calcium ion binding; Located in plasma membrane; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: EF-HAND 2 (InterPro:IPR018249), EPS15 homology (EH) (InterPro:IPR000261), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048); BEST Arabidopsis thaliana protein match is: Calcium-binding EF hand family protein (TAIR:AT1G21630.1); Has 12017 Blast hits to 4944 proteins in 443 species: Archae - 20; Bacteria - 3590; Metazoa - 3650; [...]
   
 
 0.710
AT1G21630
Calcium-binding EF hand family protein; Its function is described as calcium ion binding; Located in cytosol; Expressed in 24 plant structures; Expressed during 15 growth stages; Contains the following InterPro domains: EF-HAND 2 (InterPro:IPR018249), EPS15 homology (EH) (InterPro:IPR000261), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand-like domain (InterPro:IPR011992); BEST Arabidopsis thaliana protein match is: Calcium-binding EF hand family protein (TAIR:AT1G20760.1)
   
 
 0.710
FZL
Probable transmembrane GTPase FZO-like, chloroplastic; A new plant-specific member of the dynamin superfamily; defines a new protein class within the dynamin superfamily of membrane remodeling GTPases that regulates organization of the thylakoid network in plants. Targeted to chloroplasts and associated with thylakoid and envelope membranes as punctate structures. Knockout mutants have abnormalities in chloroplast and thylakoid morphology, including disorganized grana stacks and alterations in the relative proportions of grana and stroma thylakoids. Overexpression of FZL-GFP also confe [...]
   
 
 0.687
FTSZ1-1
Homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1; Exhibits GTPase activity. Component of the plastid division machinery that forms a contractile ring at the division site. Required for plastid division in a dose-dependent manner. Involved in blue light-induced chloroplast movements. May regulate thylakoid development; Belongs to the FtsZ family
      
 0.645
AT1G30925
Putative F-box protein At1g30925; Phospholipase Cs; Its function is described as phospholipase C activity; Involved in intracellular signaling pathway, lipid metabolic process; Located in cellular_component unknown; Contains the following InterPro domains: F-box associated domain, type 3 (InterPro:IPR013187), Phospholipase C, phosphatidylinositol-specific , X domain (InterPro:IPR000909), F-box associated interaction domain (InterPro:IPR017451); BEST Arabidopsis thaliana protein match is: F-box and associated interaction domains-containing protein (TAIR:AT1G33020.1); Has 1130 Blast hits [...]
      
 0.619
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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