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PIS1 protein (Arabidopsis thaliana) - STRING interaction network
"PIS1" - CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1 in Arabidopsis thaliana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PIS1CDP-diacylglycerol--inositol 3-phosphatidyltransferase 1; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme; Belongs to the CDP-alcohol phosphatidyltransferase class-I family (227 aa)    
Predicted Functional Partners:
PI-4KBETA1
Phosphatidylinositol 4-OH kinase beta1; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5-trisphosphate. Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB2, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB2 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway (1121 aa)
     
 
  0.971
ATSAC1B
Phosphoinositide phosphatase family protein; Mutants in this gene are unable to express female sterility in response to beta-aminobutyric acid, as wild type plants do. non-consensus AT donor splice site at exon 7, TA donor splice site at exon 10, AT acceptor splice at exon 13 (593 aa)
     
 
  0.960
SAC8
Phosphoinositide phosphatase SAC8; Phosphoinositide phosphatase that hydrolyzes PtdIns(3)P and PtdIns(4)P (588 aa)
     
 
  0.960
RHD4
Phosphoinositide phosphatase family protein; Phosphoinositide phosphatase that preferentially hydrolyzes PtdIns(4)P. Regulates the accumulation of PtdIns(4)P on membrane compartments at the tips of growing root hairs leading to proper root hair development (597 aa)
     
 
  0.960
AT1G51040
Phosphatidylinositol 4-kinase alpha 2; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (525 aa)
     
 
  0.957
PI4KA1
Phosphatidylinositol 3- and 4-kinase family protein; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. Can bind to phosphatidylinositol 4- monophosphate (PI-4-P or PtdIns4P), phosphatidylinositol 4,5- bisphosphate (PI-4,5-P2 or PtdIns4,5P2), and phosphatidic acid (PtdOH), but not to 3-phosphoinositides. May function upstream of the cold response phosphoinositide-dependent phospholipase C (PI- PLC) pathway (2028 aa)
     
 
  0.957
PI-4KBETA2
Phosphatidylinositol 4-OH kinase beta2; Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5-trisphosphate (By similarity). Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KB1, required during polarized root hair expansion and pollen tube elongation. Functions redundantly with PI4KB1 upstream of the cold response phosphoinositide-dependent phospholipase C (PI-PLC) pathway (1116 aa)
     
 
  0.950
MIOX1
Myo-inositol oxygenase 1; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in plant ascorbate biosynthesis (311 aa)
         
  0.947
MIOX5
Myo-inositol oxygenase 5; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in plant ascorbate biosynthesis; Belongs to the myo-inositol oxygenase family (314 aa)
         
  0.944
MIOX2
Myo-inositol oxygenase 2; Involved in the biosynthesis of UDP-glucuronic acid (UDP-GlcA), providing nucleotide sugars for cell-wall polymers. May be also involved in plant ascorbate biosynthesis; Belongs to the myo-inositol oxygenase family (317 aa)
         
  0.942
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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