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STRINGSTRING
HPR protein (Arabidopsis thaliana) - STRING interaction network
"HPR" - Glycerate dehydrogenase HPR, peroxisomal in Arabidopsis thaliana
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second shell of interactors
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proteins of unknown 3D structure
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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textmining
co-expression
protein homology
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HPRGlycerate dehydrogenase HPR, peroxisomal; Catalyzes the NADH-dependent reduction of hydroxypyruvate into glycerate in the photorespiratory core cycle. Mediates fatty acid beta-oxidation in germinating seeds when malate dehydrogenase is absent (387 aa)    
Predicted Functional Partners:
AGT
Serine--glyoxylate aminotransferase; Photorespiratory enzyme that catalyzes transamination reactions with multiple substrates, including asparagine. Function exclusively as a catabolic enzyme in Asn metabolism; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family (401 aa)
   
 
  0.998
AT1G80380
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Catalyzes the concluding reaction of the photorespiratory C2 cycle, an indispensable ancillary metabolic pathway to the photosynthetic C3 cycle that enables land plants to grow in an oxygen-containing atmosphere (456 aa)
   
 
  0.996
GGAT1
Glutamate--glyoxylate aminotransferase 1; Catalyzes the glutamate-glyoxylate (GGT or GGAT), alanine-glyoxylate (AGT), alanine-2-oxoglutarate (AKT) and glutamate-pyruvate (GPT) aminotransferase reactions in peroxisomes. Required for abscisic acid (ABA)- and stress-mediated responses in an H(2)O(2)-dependent manner. Function as a photorespiratory aminotransferase that modulates amino acid content during photorespiration (GGAT activity); promotes serine, glycine and citrulline metabolism in response to light (481 aa)
   
 
  0.995
GOX2
Aldolase-type TIM barrel family protein; Its function is described as glycolate oxidase activity, oxidoreductase activity, FMN binding, catalytic activity; Involved in oxidation reduction, metabolic process; Located in peroxisome; Expressed in guard cell, leaf; Contains the following InterPro domains- Aldolase-type TIM barrel (InterPro-IPR013785), FMN-dependent alpha-hydroxy acid dehydrogenase, active site (InterPro-IPR008259), FMN-dependent dehydrogenase (InterPro-IPR000262), Alpha-hydroxy acid dehydrogenase, FMN-dependent (InterPro-IPR012133); BEST Arabidopsis thaliana protein match [...] (373 aa)
   
 
  0.981
SHM1
Encodes a protein with mitochondrial serine hydroxymethyltransferase activity, which functions in the photorespiratory pathway, catalyzes the conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. Involved in controlling cell damage caused by abiotic stress, such as high light and salt and the hypersensitive defense response of plants; Belongs to the SHMT family (517 aa)
   
   
  0.969
PGLP1
2-phosphoglycolate phosphatase 1; Photorespiratory enzyme that dephosphorylates the 2- phosphoglycolate produced by the RuBisCO oxygenation reaction (362 aa)
   
   
  0.967
PMDH2
Peroxisomal NAD-malate dehydrogenase 2; Catalyzes a reversible NAD-dependent dehydrogenase reaction involved in central metabolism and redox homeostasis between organelle compartments (Probable). Peroxisomal NAD- dependent malate dehydrogenase involved in fatty acid beta- oxidation. Reoxidizes NADH from the beta-oxidation and provides NAD for the conversion of fatty acyl-CoA to acetyl-CoA. Does not participate directly in the glyoxylate cycle. Required for maintenance of photosynthetic rates under photorespiratory conditions, and carbon flow during photorespiration. Supplies NADH reduc [...] (363 aa)
   
 
  0.953
MLS
Malate synthase; Does not seem to be essential for lipid utilization and gluconeogenesis in seedlings; Belongs to the malate synthase family (562 aa)
     
 
  0.951
RCA
Ribulose bisphosphate carboxylase/oxygenase activase, chloroplastic; Activation of RuBisCO (ribulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39) involves the ATP-dependent carboxylation of the epsilon-amino group of lysine leading to a carbamate structure (474 aa)
     
   
  0.949
ICL
Isocitrate lyase; Involved in storage lipid mobilization during the growth of higher plant seedling; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family (576 aa)
     
  0.944
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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