STRINGSTRING
NAP protein (Arabidopsis thaliana) - STRING interaction network
"NAP" - NAC-like, activated by AP3/PI in Arabidopsis thaliana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAPNAC-like, activated by AP3/PI; Transcription activator that binds to, and transactivates the promoter of the abscisic aldehyde oxidase AAO3. Promotes chlorophyll degradation in leaves by enhancing transcription of AAO3, which leads to increased levels of the senescence-inducing hormone abscisic acid (ABA). Involved in the control of dehydration in senescing leaves. Binds to the DNA sequence 5’-CACGTAAGT-3’ of SAG113 promoter. SAG113 acts as negative regulator of ABA signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Transcription factor of the NAC [...] (268 aa)    
Predicted Functional Partners:
NAC6
NAC domain containing protein 6; Transcription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5’- [ACG][CA]GT[AG](5-6n)[CT]AC[AG]-3’. Promotes lateral root development. Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways. Regulates also genes during seed germination. Regulates positively aging-induced cell death. Involved in age-related resistance (ARR) against Pseudomonas syringae pv. to [...] (285 aa)
     
 
0.869
HAI1
Probable protein phosphatase 2C 78; Acts as negative regulator of abscisic acid (ABA) signaling for stomatal closure in leaves, and controls water loss during leaf senescence. Activated by the NAC029/NAP transcription factor during ABA signaling in senescing leaves. Functions as negative regulator of osmotic stress and ABA signaling. Acts as negative regulator of response to drought (413 aa)
     
   
  0.849
NYE1
Protein STAY-GREEN 1, chloroplastic; Involved in the disassembling mechanism of the intact light-harvesting complex of photosystem II (LHCII) in the thylakoid membranes. Required to trigger chlorophyll degradation during natural and dark-induced leaf senescence. Regulated at the transcriptional level by ABI3 (268 aa)
     
   
  0.714
AT1G30755
Elongation factor G, putative (DUF668); Protein of unknown function (DUF668); Contains the following InterPro domains- Protein of unknown function DUF668 (InterPro-IPR007700), Protein of unknown function DUF3475 (InterPro-IPR021864); BEST Arabidopsis thaliana protein match is- Protein of unknown function (DUF668) (TAIR-AT1G34320.1); Has 465 Blast hits to 399 proteins in 71 species- Archae - 2; Bacteria - 14; Metazoa - 66; Fungi - 16; Plants - 336; Viruses - 0; Other Eukaryotes - 31 (source- NCBI BLink) (615 aa)
     
   
  0.679
IAA14
Indole-3-acetic acid inducible 14; Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression (228 aa)
       
 
  0.669
SAG12
Senescence-associated gene 12 (SAG12) encoding a cysteine protease influenced by cytokinin, auxin, and sugars.Localized to special vacuole found during senescence called senescence associated vacuoles which are different from central vacuole in the tonoplast composition and pH (346 aa)
           
  0.668
POL
Protein phosphatase 2C family protein; Pol mutations are recessive, partial suppressors of meristem defects in strong clv1 and clv3 mutants, and nearly complete suppressors of weak clv1 mutants. Single mutants appear normal. Acts downstream of the CLV signaling pathway in meristem development and is required together with PLL1 for stem-cell maintenance through the regulation of WUS; Belongs to the PP2C family (856 aa)
           
  0.667
CDL1
Probable serine/threonine-protein kinase PBL7; Serine/threonine-protein kinase involved in the positive regulation of brassinosteroid (BR) signaling and plant growth. Phosphorylates both BSU1 and BSL1 in vitro (378 aa)
     
   
  0.655
AT5G37670
HSP20-like chaperones superfamily protein; Possesses chaperone activity; Belongs to the small heat shock protein (HSP20) family (137 aa)
           
  0.645
PI
K-box region and MADS-box transcription factor family protein; Probable transcription factor involved in the genetic control of flower development. Is required for normal development of petals and stamens in the wild-type flower. Forms a heterodimer with APETALA3 that is required for autoregulation of both AP3 and PI genes. AP3/PI heterodimer interacts with APETALA1 or SEPALLATA3 to form a ternary complex that could be responsible for the regulation of the genes involved in the flower development. AP3/PI heterodimer activates the expression of NAP (208 aa)
           
  0.641
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
Server load: low (22%) [HD]