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AT1G79870 protein (Arabidopsis thaliana) - STRING interaction network
"AT1G79870" - D-isomer specific 2-hydroxyacid dehydrogenase family protein in Arabidopsis thaliana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AT1G79870D-isomer specific 2-hydroxyacid dehydrogenase family protein; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate (HP) into glycolate and glycerate in the cytoplasm, thus providing a cytosolic bypass to the photorespiratory core cycle. Mostly active in the presence of NADPH and hydroxypyruvate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily (313 aa)    
Predicted Functional Partners:
AGT
Serine--glyoxylate aminotransferase; Photorespiratory enzyme that catalyzes transamination reactions with multiple substrates, including asparagine. Function exclusively as a catabolic enzyme in Asn metabolism; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family (401 aa)
   
 
  0.967
AT1G80380
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Catalyzes the concluding reaction of the photorespiratory C2 cycle, an indispensable ancillary metabolic pathway to the photosynthetic C3 cycle that enables land plants to grow in an oxygen-containing atmosphere (456 aa)
   
 
  0.965
GLYR1
Glyoxylate/succinic semialdehyde reductase 1; Catalyzes the NADPH-dependent reduction of glyoxylate to glycolate as well as succinic semialdehyde (SSA) to gamma- hydroxybutyrate in vitro. May function in redox homeostasis and play a role in oxidative stress tolerance by detoxifying glyoxylate and SSA generated in glycolate metabolism and GABA metabolism, respectively (289 aa)
   
 
  0.916
THO1
Nuclear matrix protein-related; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export. Contributes to the integrity of the endogenous trans-acting small interfering RNA (ta-siRNA) pathway. May process or transport a long RNA molecule so that it can be a template for secondary siRNA production. May participate in the trafficking of siRNA precursors to the ARGONAUTE catalytic center. Required for the generation of functional messenger ribonucleoproteins (mRNPs). Plays an important roles in plant innate immunity (599 aa)
           
  0.904
ICL
Isocitrate lyase; Involved in storage lipid mobilization during the growth of higher plant seedling; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family (576 aa)
     
  0.903
MLS
Malate synthase; Does not seem to be essential for lipid utilization and gluconeogenesis in seedlings; Belongs to the malate synthase family (562 aa)
     
 
  0.891
GLYR2
Glyoxylate/succinic semialdehyde reductase 2, chloroplastic; Catalyzes the NADPH-dependent reduction of glyoxylate to glycolate as well as succinic semialdehyde (SSA) to gamma- hydroxybutyrate in vitro. May function in redox homeostasis and play a role in oxidative stress tolerance by detoxifying glyoxylate and SSA generated in glycolate metabolism and GABA metabolism, respectively; Belongs to the 3-hydroxyisobutyrate dehydrogenase family. NP60 subfamily (358 aa)
       
  0.888
GGAT1
Glutamate--glyoxylate aminotransferase 1; Catalyzes the glutamate-glyoxylate (GGT or GGAT), alanine-glyoxylate (AGT), alanine-2-oxoglutarate (AKT) and glutamate-pyruvate (GPT) aminotransferase reactions in peroxisomes. Required for abscisic acid (ABA)- and stress-mediated responses in an H(2)O(2)-dependent manner. Function as a photorespiratory aminotransferase that modulates amino acid content during photorespiration (GGAT activity); promotes serine, glycine and citrulline metabolism in response to light (481 aa)
   
 
  0.872
HPR
Glycerate dehydrogenase HPR, peroxisomal; Catalyzes the NADH-dependent reduction of hydroxypyruvate into glycerate in the photorespiratory core cycle. Mediates fatty acid beta-oxidation in germinating seeds when malate dehydrogenase is absent (387 aa)
   
   
0.858
AOAT2
Alanine-2-oxoglutarate aminotransferase 2; Catalyzes the Glu-glyoxylate aminotransferase (GGT), Ala-glyoxylate aminotransferase (AGT), Ala-2-oxoglutarate aminotransferase (AKT) and Glu-pyruvate aminotransferase (GPT) reactions in peroxisomes; Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily (481 aa)
   
 
  0.831
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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