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RECA2 protein (Arabidopsis thaliana) - STRING interaction network
"RECA2" - DNA repair protein recA homolog 3, mitochondrial in Arabidopsis thaliana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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RECA2DNA repair protein recA homolog 3, mitochondrial; Involved in recombination ability and DNA strand transfer activity (430 aa)    
Predicted Functional Partners:
POLGAMMA1
DNA polymerase I B, chloroplastic/mitochondrial; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (By similarity). Required for DNA replication and accumulation in plastids and mitochondria (1049 aa)
   
 
  0.925
RAD51C
RAS associated with diabetes protein 51C; Encodes a protein similar to RAD51C involved in double stranded break repair via homologous recombination. Sensitive to DSB induced by Mitomycin C and gamma irradiation, interacts with Atxrcc3 in yeast two-hybrid assay. Required for female meiosis but not critical for mitosis under normal conditions; Belongs to the RecA family. RAD51 subfamily (387 aa)
       
 
  0.914
SRS2
P-loop containing nucleoside triphosphate hydrolases superfamily protein; Encodes a homolog of the yeast SRS2 (Suppressor of RAD Six-screen mutant 2) helicase. The Arabidopsis SRS2 is a functional 3- to 5-helicase. Biochemical studies show that SRS2 disrupts recombinogenic DNA intermediates and facilitates single strand annealing (1149 aa)
   
 
  0.898
UVH3
5’-3’ exonuclease family protein; Putative single-stranded DNA endonuclease involved in nucleotide excision repair (NER) of UV- and oxidative damaged DNA. May make the 3’-incision step in NER. Seems to play a role in senescence program; Belongs to the XPG/RAD2 endonuclease family. XPG subfamily (1479 aa)
   
 
  0.882
XRCC3
Homolog of X-ray repair cross complementing 3 (XRCC3); Plays essential roles in DNA damage repair in both somatic and meiotic cells. It is important for postsynaptic events following pachytene in meiosis. It is also required for DNA cross- links repair and is involved in double strand breaks (DSBs) repair (304 aa)
       
 
  0.880
THY-2
Bifunctional dihydrofolate reductase-thymidylate synthase 2; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (565 aa)
   
   
  0.878
AT2G21550
Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism (492 aa)
   
   
  0.878
THY-1
Bifunctional dihydrofolate reductase-thymidylate synthase 1; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism. Can play two different roles depending on the source of dihydrofolate- de novo synthesis of tetrahydrofolate or recycling of the dihydrofolate released as one of the end products of the TS catalyzed reaction. Catalyzes an essential reaction for de novo glycine and purine synthesis, DNA precursor synthesis, and for the conversion of dUMP to dTMP; In the C-terminal section; belongs to the thymidylate synthase family (519 aa)
   
   
  0.878
AT2G01440
ATP-dependent DNA helicase homolog RECG, chloroplastic; Critical role in recombination and DNA repair (973 aa)
     
   
  0.866
BRCA2B
Protein BREAST CANCER SUSCEPTIBILITY 2 homolog B; Involved in double-strand break repair and/or homologous recombination by mediating RAD51- and DMC1-facilitated DNA repair. Plays an essential role in both somatic and meiotic homologous recombination. Is crucial for the formation of RAD51 and DMC1 foci during male meiotic homologous recombination in prophase I (1155 aa)
     
 
  0.858
Your Current Organism:
Arabidopsis thaliana
NCBI taxonomy Id: 3702
Other names: A. thaliana, Arabidopsis thaliana, Arabidopsis thaliana (L.) Heynh., mouse-ear cress, thale cress, thale-cress
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